ChemicalBook > CAS DataBase List > Hydroxy-PEG3-PFP ester
Hydroxy-PEG3-PFP ester
Hydroxy-PEG3-PFP ester
- CAS No.1807537-40-1
- Chemical Name:Hydroxy-PEG3-PFP ester
- CBNumber:CB53062512
- Molecular Formula:C15H17F5O6
- Formula Weight:388.28
- MOL File:1807537-40-1.mol
Hydroxy-PEG3-PFP ester Property
- Boiling point 440.3±45.0 °C(Predicted)
- Density 1.385±0.06 g/cm3(Predicted)
- pka 14.36±0.10(Predicted)
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
Hydroxy-PEG3-PFP ester Chemical Properties,Usage,Production
- Uses Hydroxy-PEG3-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
- Biological Activity Hydroxy-PEG3-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
- IC 50 PEGs
- References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Hydroxy-PEG3-PFP ester Preparation Products And Raw materials
Raw materials
Preparation Products
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1807537-40-1, Hydroxy-PEG3-PFP esterRelated Search:
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- 羟基-三聚乙二醇-C2-五氟苯酚酯
- 1807537-40-1
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