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Prasugrel Hydrochloride

Prasugrel Hydrochloride Structure
Prasugrel Hydrochloride
  • CAS No.389574-19-0
  • Chemical Name:Prasugrel Hydrochloride
  • CBNumber:CB52465251
  • Molecular Formula:C20H20FNO3S.ClH
  • Formula Weight:409.907
  • MOL File:389574-19-0.mol
Prasugrel Hydrochloride Property
  • Melting point >173?C (dec.)
  • storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
  • solubility Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
  • form Solid
  • color White to Pale Brown
  • InChI InChI=1S/C20H20FNO3S.ClH/c1-12(23)25-18-10-14-11-22(9-8-17(14)26-18)19(20(24)13-6-7-13)15-4-2-3-5-16(15)21;/h2-5,10,13,19H,6-9,11H2,1H3;1H
  • InChIKey JALHGCPDPSNJNY-UHFFFAOYSA-N
  • SMILES N1(CCC2SC(OC(C)=O)=CC=2C1)C(C1C=CC=CC=1F)C(=O)C1CC1.Cl
  • FDA UNII G89JQ59I13
  • UNSPSC Code 41116107
  • NACRES NA.24
Safety
  • HS Code  :2934990002
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H335
  • Precautionary statements P261-P280-P301+P312-P302+P352-P305+P351+P338

Prasugrel Hydrochloride Chemical Properties,Usage,Production

  • Description Prasugrel hydrochloride (PCR 4099 hydrochloride), a thienopyridine and proagent, inhibits platelet function. Prasugrel hydrochloride is an orally active and potent P2Y12 receptor antagonist and inhibits ADP-induced platelet aggregation.
  • Chemical Properties White to Off-White Solid
  • Uses A novel antiplatelet agent; it is a third-generation thienopyridine. Antiplatelet agent Prasugrel showed greater platelet inhibition and decreased incidence of ischemic events than Clopidogrel but may induce increased incidence of bleeding in patient with acute coronary syndrome
  • in vivo In rat platelets, Prasugrel hydrochloride active metabolite inhibits in vitro platelet aggregation induced by adenosine ADP (10μM) with an IC50 value of 1.8 μM. Prasugrel hydrochloride acts faster and is significantly more potent than Clopidogrel in vivo. Prasugrel hydrochloride is an inactive prodrug that requires metabolic processing in vivo to generate the active antiplatelet metabolite. Prasugrel hydrochloride is rapidly absorbed from the gut. After oral administration of standard-loading doses of 60 mg, maximum plasma levels of the active metabolite are achieved within 1 h, effective, maximum inhibition of platelet aggregation at 1-2 h.
  • IC 50 P2Y12 Receptor
Prasugrel Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Prasugrel Hydrochloride Suppliers
Global(294)Suppliers
  • Supplier：
    Henan Tianfu Chemical Co.,Ltd.
  • Tel：+86-0371-55170693<br/>+86-19937530512
  • Email：info@tianfuchem.com
  • Country：China
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  • Supplier：
    career henan chemical co
  • Tel：+86-0371-86658258<br/>+8613203830695
  • Email：sales@coreychem.com
  • Country：China
  • ProdList：29858
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  • Supplier：
    Biochempartner
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  • Email：candy@biochempartner.com
  • Country：CHINA
  • ProdList：965
  • Advantage：58
Prasugrel Hydrochloride Spectrum
389574-19-0, Prasugrel HydrochlorideRelated Search:
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  • C20H20FNO3SClH
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  • Prasugrel HydrochlorideQ: What is Prasugrel Hydrochloride Q: What is the CAS Number of Prasugrel Hydrochloride Q: What are the applications of Prasugrel Hydrochloride
  • Prasugrel Hydrochloride (PCR 4099
  • 5-(2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate hydrochloride
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  • acetic acid [5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-yl] ester
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  • Unii-G89jq59I13

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