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BMS-986299

BMS-986299 Structure
BMS-986299
  • CAS No.2242952-69-6
  • Chemical Name:BMS-986299
  • CBNumber:CB48871220
  • Molecular Formula:C18H19N7O
  • Formula Weight:349.39
  • MOL File:2242952-69-6.mol
BMS-986299 Property
  • Boiling point 757.5±60.0 °C(Predicted)
  • Density 1.407±0.06 g/cm3(Predicted)
  • storage temp. Store at -20°C
  • pka 11.46±0.40(Predicted)
  • form Solid
  • color White to off-white
  • FDA UNII VS58MO4P47
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

BMS-986299 Chemical Properties,Usage,Production

  • Uses BMS-986299 (compound 112) is a first-in-class NLRP3 inflammasome agonist with an EC50 of 1.28 μM. (patent WO2018152396A1).
  • IC 50 NLRP3: 1.28 μM (EC50)
  • References [1] Gary Glick, et al. Substituted imidazo-quinolines as nlrp3 modulators. WO2018152396A1.
    [2] Gao G, et al., Cyclovirobuxine D Ameliorates Experimental Diabetic Cardiomyopathy by Inhibiting Cardiomyocyte Pyroptosis via NLRP3 in vivo and in vitro. Front Pharmacol. 2022 Jul 5;13:906548. DOI:10.3389/fphar.2022.906548
BMS-986299 Preparation Products And Raw materials
Raw materials
Preparation Products
BMS-986299 Suppliers
Global(33)Suppliers
  • Supplier：
    TargetMol Chemicals Inc.
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  • Email：marketing@targetmol.com
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    Aladdin Scientific
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  • Supplier： BOC Sciences
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  • Supplier： ATK CHEMICAL COMPANY LIMITED
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  • Email：mandy@atkchemical.com
  • Country：China
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BMS-986299 Spectrum
2242952-69-6, BMS-986299Related Search:
  • 抑制剂
  • 合成有机化合物配体
  • 化合物BMS986299,10 MM DMSO 溶液
  • N-((4-氨基-7-(1H-吡唑-5-基)-3H-咪唑并[4,5-C]喹啉-2-基)甲基)-N-乙基乙酰胺
  • 化合物BMS986299
  • BMS986299
  • 2242952-69-6
  • BMS986299, 10 mM in DMSO
  • N-((4-Amino-7-(1H-pyrazol-5-yl)-3H-imidazo[4,5-c]quinolin-2-yl)methyl)-N-ethylacetamide
  • Acetamide, N-[[4-amino-7-(1H-pyrazol-3-yl)-3H-imidazo[4,5-c]quinolin-2-yl]methyl]-N-ethyl-
  • BMS-986299

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