ChemicalBook > CAS DataBase List > 4-Hydroxy 4-Dedimethylamino Afatinib
4-Hydroxy 4-Dedimethylamino Afatinib
- CAS No.2121530-37-6
- Chemical Name:4-Hydroxy 4-Dedimethylamino Afatinib
- CBNumber:CB44806714
- Molecular Formula:C22H20ClFN4O4
- Formula Weight:458.87
- MOL File:2121530-37-6.mol
4-Hydroxy 4-Dedimethylamino Afatinib Property
- Boiling point 714.713±60.00 °C(Press: 760.00 Torr)(predicted)
- Density 1.484±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
- pka 11.521±0.43(predicted)
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
4-Hydroxy 4-Dedimethylamino Afatinib Chemical Properties,Usage,Production
- Uses (2E)?-N-?[4-?[(3-?chloro-?4-?fluorophenyl)?amino]?-?7-?[[(3S)?-?tetrahydro-?3-?furanyl]?oxy]?-?6-?quinazolinyl]?-?4-?hydroxy-2-?butenamide is an impurity of Afatinib (A355300), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.
4-Hydroxy 4-Dedimethylamino Afatinib Preparation Products And Raw materials
Raw materials
Preparation Products
Global(26)Suppliers
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2121530-37-6, 4-Hydroxy 4-Dedimethylamino AfatinibRelated Search:
- Afatinib Impurity 3 Afatinib Impurity 19 Afatinib Impurity 7 Afatinib IMpurity F R-afatinib Afatinib Afatinib Impurity 10 N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine AfatinibHydrolytic impurity Afatinib Impurity 15 Afatinib Impurity 2 Afatinib Impurity 18 Afatinib Impurity 6 Afatinib IMpurity E Afatinib iMpurity Afatinib Impurity 9 Afatinib Impurity 14 Afatinib Impurity 17
- 原料药-杂质对照品
- 杂质
- 阿法替尼-4-羟基杂质
- (2E)-N-[4-[(3-氯-4-氟苯基)氨基]-7-[[(3S)-四氢-3-呋喃基]氧基]-6-喹唑啉基]-4-羟基-2-丁烯酰胺
- 马来酸阿法替尼杂质3
- 2121530-37-6
- Lansoprazole Impurity 73
- 1,3-dimethyl-52-nitrosourea
- (2E)?-N-?[4-?[(3-?chloro-?4-?fluorophenyl)?amino]?-?7-?[[(3S)?-?tetrahydro-?3-?furanyl]?oxy]?-?6-?quinazolinyl]?-?4-?hydroxy-2-?butenamide
- 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-hydroxy-, (2E)-
- Afatinib Maleate Acid Impurity 3
- Afatinib 4-Hydroxy Analog
- Afatinib impurity 2/4-Hydroxy 4-Dedimethylamino Afatinib/(2E)-N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-hydroxy-2-butenamide
- 4-Hydroxy 4-Dedimethylamino Afatinib
