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5-Chloro-8-hydroxyquinoline

5-Chloro-8-hydroxyquinoline Structure
5-Chloro-8-hydroxyquinoline
  • CAS No.130-16-5
  • Chemical Name:5-Chloro-8-hydroxyquinoline
  • CBNumber:CB4434834
  • Molecular Formula:C9H6ClNO
  • Formula Weight:179.6
  • MOL File:130-16-5.mol
5-Chloro-8-hydroxyquinoline Property
  • Melting point 122-124 °C(lit.)
  • Boiling point 348.7±22.0 °C(Predicted)
  • Density 1.2364 (rough estimate)
  • vapor pressure 0.003Pa at 25℃
  • refractive index 1.5330 (estimate)
  • storage temp. Sealed in dry,Room Temperature
  • solubility 0.019g/l (experimental)
  • form Powder
  • pka 3.77±0.10(Predicted)
  • color Light green to gray
  • Sensitive Light Sensitive
  • Merck 14,2422
  • BRN 5289
  • InChIKey RWPWQYXFGFYJBA-UHFFFAOYSA-N
  • CAS DataBase Reference 130-16-5(CAS DataBase Reference)
  • FDA 21 CFR 310.545
  • EWG's Food Scores 1
  • FDA UNII BPF36H1G6S
  • NIST Chemistry Reference 8-Quinolinol, 5-chloro-(130-16-5)
  • EPA Substance Registry System 8-Quinolinol, 5-chloro- (130-16-5)
  • UNSPSC Code 12352100
  • NACRES NA.22
Safety
  • Hazard Codes  :Xi
  • Risk Statements  :36/37/38
  • Safety Statements  :26-36-24/25
  • WGK Germany  :3
  • RTECS  :VC4590000
  • TSCA  :Yes
  • HS Code  :29334990
  • NFPA 704:
    0
    2 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335-H410
  • Precautionary statements P261-P264-P271-P273-P302+P352-P305+P351+P338
5-Chloro-8-hydroxyquinoline Price More Price(3)
  • Brand: Sigma-Aldrich(India)
  • Product number: C47000
  • Product name : 5-Chloro-8-quinolinol
  • Purity: 95%
  • Packaging: 100G
  • Price: ₹6646.55
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: C0645
  • Product name : 5-Chloro-8-hydroxyquinoline
  • Purity: min. 98.0 %
  • Packaging: 25G
  • Price: ₹2500
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: C0645
  • Product name : 5-Chloro-8-hydroxyquinoline
  • Purity: min. 98.0 %
  • Packaging: 250G
  • Price: ₹9400
  • Updated: 2022/05/26
  • Buy: Buy

5-Chloro-8-hydroxyquinoline Chemical Properties,Usage,Production

  • Chemical Properties light green to grey powder
  • Uses Dermofungin, is an impurity of Cioquinol, which is an antifungal and antiprotozoal drug.
  • Uses antibacterial, antifungal
  • Definition ChEBI: Cloxiquine is a member of quinolines and an organochlorine compound.
  • Synthesis Reference(s) The Journal of Organic Chemistry, 70, p. 8590, 2005 DOI: 10.1021/jo051191x
  • in vitro Cloxiquine (cloxyquin) exhibits antituberculosis activities, with MICs ranging from 0.062 to 0.25 μg/mL against 9 standard strains and 150 Mycobacterium tuberculosis .
    Cloxiquine (0.5-10 μM; 24 h) suppresses both B16F10 and A375 cell growth in a dose-dependent manner.|
    Cloxiquine (0.5-10 μM; 24 h) inhibits the migration of B16F10 and A375 cells.
    Cloxiquine (0.5-2.5 μM; 24 h) suppresses glycolysis in B16F10 cells.
  • in vivo Cloxiquine (5-25 mg/kg; i.p. daily for 8 d) suppresses tumor growth in a mouse B16F10 melanoma xenograft model.
    Cloxiquine (5-25 mg/kg; i.p. daily for 14 d) suppresses tumor metastasis in mouse B16F10 melanoma lung metastatic model.
5-Chloro-8-hydroxyquinoline Preparation Products And Raw materials
Raw materials
Preparation Products
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5-Chloro-8-hydroxyquinoline Spectrum
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