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m-PEG3-Sulfone-PEG4-propargyl

m-PEG3-Sulfone-PEG4-propargyl Structure
m-PEG3-Sulfone-PEG4-propargyl
  • CAS No.2055041-02-4
  • Chemical Name:m-PEG3-Sulfone-PEG4-propargyl
  • CBNumber:CB43163016
  • Molecular Formula:C18H34O9S
  • Formula Weight:426.52
  • MOL File:2055041-02-4.mol
m-PEG3-Sulfone-PEG4-propargyl Property
  • Boiling point 536.0±50.0 °C(Predicted)
  • Density 1.137±0.06 g/cm3(Predicted)
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

m-PEG3-Sulfone-PEG4-propargyl Chemical Properties,Usage,Production

  • Description m-PEG3-Sulfone-PEG4-propargyl is a sulfonated PEG linker containing a propargyl group. The propargyl groups can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages. The hydrophilic PEG spacer increases solubility in aqueous media.
  • Uses m-PEG3-Sulfone-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. m-PEG3-Sulfone-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • IC 50 PEGs
  • References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
m-PEG3-Sulfone-PEG4-propargyl Preparation Products And Raw materials
Raw materials
Preparation Products
m-PEG3-Sulfone-PEG4-propargyl Suppliers
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m-PEG3-Sulfone-PEG4-propargyl Spectrum
2055041-02-4, m-PEG3-Sulfone-PEG4-propargylRelated Search:
  • C18H34O9S
  • 甲氧基-三聚乙二醇-砜-四聚乙二醇-丙炔
  • M-三聚乙二醇-SULFONE-四聚乙二醇-炔基
  • 甲基-三聚乙二醇-砜-四聚乙二醇-炔基
  • 2055041-02-4
  • 2,5,8,14,17,20,23-Heptaoxa-11-thiahexacos-25-yne, 11,11-dioxide
  • m-PEG3-Sulfone-PEG4-propargyl

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