TM5007
- Product NameTM5007
- CAS342595-05-5
- CBNumberCB43067585
- MFC24H20N2O6S4
- MW560.69
- MOL File342595-05-5.mol
Chemical Properties
| Boiling point: | 781.7±60.0 °C(Predicted) |
| Density | 1.544±0.06 g/cm3(Predicted) |
| pka | 3.93±0.40(Predicted) |
TM5007 Chemical Properties,Usage,Production
Uses
TM5007 is a poent and orally active inhibitor of plasminogen activator inhibitor-1 (PAI-1) with an IC50 of 29 μM. TM5007 enhance fibrinolysis activity and inhibits coagulation. TM5007 also prevents the fibrotic process initiated by bleomycin in mouse lung[1].References
[1] Izuhara Y, et al. Inhibition of plasminogen activator inhibitor-1: its mechanism and effectiveness on coagulation and fibrosis. Arterioscler Thromb Vasc Biol. 2008 Apr;28(4):672-7. DOI:10.1161/ATVBAHA.107.157479TM5007 Suppliers
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