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soyosaponin Ab

soyosaponin Ab Structure
soyosaponin Ab
  • CAS No.118194-13-1
  • Chemical Name:soyosaponin Ab
  • CBNumber:CB42672946
  • Molecular Formula:C67H104O33
  • Formula Weight:1437.52
  • MOL File:118194-13-1.mol
soyosaponin Ab Property
  • Melting point 253-256℃
  • Density 1.49±0.1 g/cm3(Predicted)
  • pka 2.76±0.70(Predicted)
  • form Solid
  • color White to off-white
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

soyosaponin Ab Chemical Properties,Usage,Production

  • Uses Soyosaponin Ab is a cytotoxic agent and acts as an immunomodulatory agent.
  • in vivo

    Soyasaponin Ab (10-20 mg/kg; p.o.; daily for 5 days) shows inhibitory effect in 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colitis in male ICR mice[3].
    Soyasaponin Ab (5-40 mg/kg; p.o.; one hour before the trial) significantly prevents Scopolamine (HY-N0296)-induced memory impairment in male ICR mice[4].

    Animal Model:Male ICR mice (18-22 g, 5 weeks)[4]
    Dosage:5, 10, 20, 40 mg/kg
    Administration:Oral gavage (p.o.); One hour before the trial, and memory impairment was induced by intraperitoneal injection of Scopolamine (0.9 mg/kg) 30 min after oral administrations of test agents.
    Result:Restored memory impairment to 86% at a dose of 10 mg/kg of untreated normal control mice in the passive avoidance task. Restored spontaneous alteration, which was lowered by Scopolamine on the Y-maze task. Significantly shortened the escape latencies on the fifth day.
    Animal Model:Male institute of cancer research (ICR) mice (20-22 g, 4 weeks)[3]
    Dosage:10, 20 mg/kg
    Administration:Oral gavage (p.o.); daily for 5 days
    Result:Inhibited TNBS-induced body weight reduction, colon shortening, macroscopic score, and myeloperoxidase activity. Inhibited the expression of pro-inflammatory cytokines (TNF-α, IL-1β, IL-6). Ameliorated changes of TNBS-treated mouse colons which showed increased neutrophils, massive bowel edema, dense infiltration of the superficial layers of the mucosa, and epithelial cell disruption by large ulcerations. Inhibited the expression of TLR4, COX-2, and iNOS and the phosphorylation of IRAK1, IKK-β and p65, although it reversed IRAK-1 expression.
soyosaponin Ab Preparation Products And Raw materials
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soyosaponin Ab Spectrum
118194-13-1, soyosaponin AbRelated Search:
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  • reference standards from Chinese medicinal herbs (TCM).
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  • 标准品，对照品
  • 标准品 -中药标准品
  • 分析试剂标准品
  • 对照品
  • 对照品
  • 标准品-对照品
  • 植物提取物
  • 标准品
  • 大豆皂苷AB/三萜皂苷
  • 豆属ASAPONINAB.
  • 大豆皂苷AB对照品
  • 大豆皂苷AB标准品
  • 大豆皂苷AB
  • 118194-13-1
  • inhibit,Soyasaponin Ab,Inhibitor
  • β-D-Glucopyranosiduronic acid, (3β,4β,21β,22β)-21,23-dihydroxy-22-[[3-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-α-L-arabinopyranosyl]oxy]olean-12-en-3-yl O-β-D-glucopyranosyl-(1→2)-O-β-D-galactopyranosyl-(1→2)-
  • Soyasaponin Ab Acetylsoyasaponin A1
  • Soyasaponin Ab
  • Acetylsoyasaponin A1
  • soyosaponin Ab

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