Entereg-d5

Uses

Labelled Alvimopan. A peripheral μ-opioid receptor antagonist. Gastroprokinetic.

References

[1] BERTRAND LE BOURDONNEC . Novel trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidines as μ opioid receptor antagonists with improved opioid receptor selectivity profiles[J]. Bioorganic & Medicinal Chemistry Letters, 2008, 18 6: Pages 2006-2012. DOI: 10.1016/j.bmcl.2008.01.106
[2] B GREENWOOD-VAN MEERVELD. Preclinical studies of opioids and opioid antagonists on gastrointestinal function.[J]. Neurogastroenterology and Motility, 2004, 16 Suppl 2: 46-53. DOI: 10.1111/j.1743-3150.2004.00555.x