ChemicalBook > CAS DataBase List > S-Methyl-L-cysteine
S-Methyl-L-cysteine
S-Methyl-L-cysteine
- CAS No.1187-84-4
- Chemical Name:S-Methyl-L-cysteine
- CBNumber:CB4154282
- Molecular Formula:C4H9NO2S
- Formula Weight:135.18
- MOL File:1187-84-4.mol
S-Methyl-L-cysteine Property
- Melting point ~240 °C (dec.)
- Boiling point 300.3±37.0 °C(Predicted)
- alpha -29.5 º (c=1,water)
- Density 1.149 (estimate)
- refractive index -30 ° (C=2, H2O)
- storage temp. Keep in dark place,Sealed in dry,Store in freezer, under -20°C
- solubility Aqueous Acid (Slightly, Sonicated), Aqueous Base (Sparingly, Sonicated)
- pka pK1:8.97 (25°C)
- form Solid
- color White to Off-White
- BRN 1721675
- LogP 0.380 (est)
- CAS DataBase Reference 1187-84-4(CAS DataBase Reference)
- EWG's Food Scores 1
- FDA UNII A34I1H07YM
- NIST Chemistry Reference s-Methyl-L-cysteine(1187-84-4)
- UNSPSC Code 12352209
- NACRES NA.26
Safety
- Hazard Codes :Xn
- Risk Statements :22
- Safety Statements :22-24/25-36/37/39-26
- WGK Germany :3
- HS Code :29309090
-
NFPA 704:
0 1 0
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H315-H335-H319-H302
- Precautionary statements P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
S-Methyl-L-cysteine Price
More Price(4)
- Brand: Sigma-Aldrich(India)
- Product number: M6626
- Product name : S-Methyl-L-cysteine
- Purity: substrate for methionine sulfoxide reductase A
- Packaging: 5G
- Price: ₹9038.88
- Updated: 2022/06/14
- Buy: Buy
- Brand: Sigma-Aldrich(India)
- Product number: M6626
- Product name : S-Methyl-L-cysteine
- Purity: substrate for methionine sulfoxide reductase A
- Packaging: 25G
- Price: ₹27592.93
- Updated: 2022/06/14
- Buy: Buy
- Brand: Sigma-Aldrich(India)
- Product number: M6626
- Product name : S-Methyl-L-cysteine
- Purity: substrate for methionine sulfoxide reductase A
- Packaging: 100G
- Price: ₹67006.75
- Updated: 2022/06/14
- Buy: Buy
- Brand: TCI Chemicals (India)
- Product number: M0233
- Product name : S-Methyl-L-cysteine
- Purity:
- Packaging: 5G
- Price: ₹6200
- Updated: 2022/05/26
- Buy: Buy
S-Methyl-L-cysteine Chemical Properties,Usage,Production
- Chemical Properties white to light beige fine crystalline powder
- Uses S-Methyl-L-cysteine is a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA). It has been studied as a theurapeutic for neurodegenerative diseases including Parkinson′s.
- Definition ChEBI: A cysteine derivative that is L-cysteine in which the hydrogen attached to the sulfur is replaced by a methyl group.
-
Biological Activity
S-Methyl-L-cysteine (SMLC) is a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA). SMLC is naturally present in garlic, cabbage, and turnips and has been studied as a theurapeutic for neurodegenerative diseases including Parkinsonμs.
When used as a dietary supplement in the Drosphilia model of PD, SMLC increases the efficacy of the MRSA catalytic antioxidant system by providing additional substrate available leading to increased resistance to oxidative stress. - Purification Methods Likely impurities are cysteine and S-methyl-dl-cysteine. Crystallise it from H2O by adding 4volumes of EtOH. It also crystallises from MeOH with m 234-236o(dec), but after sublimation i t has m 267-270o and [] 27D -31.6o (c 1, H2O). [Rinderknecht et al. Helv Chim Acta 41 1, 10 1958, Theodoropoulos Acta Chem Scand 13 383 1959, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p 1904 1961, Beilstein 4 IV 3145.]
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- C4H9NO2S
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- S-Methyl-<sc>L</sc>-cysteine
- S-Methyl-L-cysteine, 10 mM in DMSO
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- Methylcysteine
- H-CYS(ME)-OH
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- (2R)-2-ammonio-3-(methylthio)propanoate
- SMLC
- S-Methyl-L-cysteine substrate for Methionine sulfoxide reductase A
- S-Methyl-L-cysteine, 99+% 10GR
- DL-S-Methyl- Cys-OH DL-S-Methyl-cysteine
- METHYL-L-CYSTEINE, S-(RG)
- (2R)-2-Amino-3-methylsulfanylpropanoic acid
- S-METHYL-L-CYSTEINE/ H-CYS(ME)-OH