ChemicalBook > CAS DataBase List > 2,4-Lutidine

2,4-Lutidine

CAS No.108-47-4
Chemical Name:2,4-Lutidine
CBNumber:CB3852754
Molecular Formula:C7H9N
Formula Weight:107.15
MOL File:108-47-4.mol

2,4-Lutidine Property

Melting point -60 °C (lit.)
Boiling point 159 °C (lit.)
Density 0.927 g/mL at 25 °C (lit.)
vapor pressure 3.28hPa at 25℃
FEMA 4389 | 2,4-DIMETHYLPYRIDINE
refractive index n20/D 1.499(lit.)
Flash point 99 °F
storage temp. Flammables area
solubility 350g/l
form Liquid
pka 6.99(at 25℃)
color Colorless to Light yellow to Light orange
Odor at 0.01 % in dipropylene glycol. smoky phenolic
Odor Type smoky
Water Solubility 15 g/100 mL (20 ºC)
Sensitive Hygroscopic
JECFA Number 2151
BRN 1506
Dielectric constant 9.5999999999999996
InChIKey JYYNAJVZFGKDEQ-UHFFFAOYSA-N
LogP 1.9
CAS DataBase Reference 108-47-4(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) 2,4-DIMETHYLPYRIDINE
EWG's Food Scores 1
FDA UNII 83903UJ0WW
NIST Chemistry Reference Pyridine, 2,4-dimethyl-(108-47-4)
EPA Substance Registry System 2,4-Dimethylpyridine (108-47-4)
UNSPSC Code 85151701
NACRES NA.22

Safety

Hazard Codes :T,F,Xi
Risk Statements :10-23/24/25-36/37/38-25-20/21-20/21/22
Safety Statements :16-26-36/37/39-45
RIDADR :UN 1992 3/PG 3
WGK Germany :3
RTECS :OK9400000
F :8
TSCA :Yes
HazardClass :3
PackingGroup :III
HS Code :29333999

NFPA 704:

	2
3		1

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordDanger
Hazard statements H226-H301+H311+H331-H315-H319-H335
Precautionary statements P210-P280-P301+P310-P303+P361+P353-P304+P340+P311-P305+P351+P338

2,4-Lutidine Price More Price(8)

Brand: Sigma-Aldrich(India)
Product number: L3609
Product name : 2,4-Lutidine
Purity: 99%
Packaging: 5ML
Price: ₹1796.95
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: L3609
Product name : 2,4-Lutidine
Purity: 99%
Packaging: 100ML
Price: ₹10078.08
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: L3609
Product name : 2,4-Lutidine
Purity: 99%
Packaging: 500ML
Price: ₹21909.8
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 68223
Product name : 2,4-Lutidine
Purity: analytical standard
Packaging: 1ML
Price: ₹6148.6
Updated: 2022/06/14
Buy: Buy

Brand: ALFA India
Product number: ALF-B22913-22
Product name : 2,4-Lutidine, 98+%
Purity:
Packaging: 100g
Price: ₹6827
Updated: 2022/05/26
Buy: Buy

2,4-Lutidine Chemical Properties,Usage,Production

Chemical Properties Colorless to pale-yellow clear liquid.
Chemical Properties Clear pale yellow liquid, discoloring over time
Uses 2,4-Lutidine, can be used as a building block in the synthesis of various chemical compounds. It is also used tobacco and aroma component.
Definition ChEBI: 2,4-Dimethylpyridine is a member of methylpyridines.
Aroma threshold values High strength odor, recommend smelling in a 0.01% solution or less.
Purification Methods Dry it with Linde type 5A molecular sieves, BaO or sodium, and fractionally distil it. The distillate (200g) is heated with *benzene (500mL) and conc HCl (150mL) in a Dean and Stark apparatus on a water bath until water no longer separates, and the temperature just below the liquid reaches 80o. When cold, the supernatant *benzene is decanted, and the 2,4-lutidine hydrochloride, after washing with a little *benzene, is dissolved in water (350mL). After removing any *benzene by steam distillation, an aqueous solution of NaOH (80g) is added, and the free lutidine is steam distilled. It is isolated by saturating the distillate with solid NaOH and distilling it through a short column. The precipitation cycle is repeated, then the final distillate is partly frozen in an apparatus at -67.8-68.5o (cooled by acetone/CO2). The crystals are collected, then melted and distilled. [Kyte et al. J Chem Soc 4454 1960.] Alternative purifications are via the picrate m 183-184o (from H2O). [Clarke & Rothwell J Chem Soc 1885 1960], or the hydrobromide [Warnhoff J Org Chem 27 4587 1962]. The latter is precipitated from a solution of lutidine in *benzene by passing dry HBr gas: the salt is recrystallised from CHCl3/methyl ethyl ketone, then decomposed with NaOH, and the free base is extracted into Et2O, dried, evaporated and the residue is distilled. [Beilstein 20 H 244, 20 II 180, 20 III/IV 2718, 20/6 V 19.]