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4-Nitro-1-naphthol

4-Nitro-1-naphthol Structure
4-Nitro-1-naphthol
  • CAS No.605-62-9
  • Chemical Name:4-Nitro-1-naphthol
  • CBNumber:CB3373545
  • Molecular Formula:C10H7NO3
  • Formula Weight:189.17
  • MOL File:605-62-9.mol
4-Nitro-1-naphthol Property
  • Melting point 165-168°C
  • Boiling point 398.8±25.0 °C(Predicted)
  • Density 1.413±0.06 g/cm3(Predicted)
  • storage temp. under inert gas (nitrogen or Argon) at 2-8°C
  • form powder to crystal
  • pka 6.22±0.40(Predicted)
  • color Light yellow to Brown
  • BRN 1959672
  • CAS DataBase Reference 605-62-9(CAS DataBase Reference)
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H335-H302-H319
  • Precautionary statements P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
4-Nitro-1-naphthol Price More Price(1)
  • Brand: TCI Chemicals (India)
  • Product number: N0672
  • Product name : 4-Nitro-1-naphthol
  • Purity: min. 97.0 %
  • Packaging: 5G
  • Price: ₹10100
  • Updated: 2022/05/26
  • Buy: Buy

4-Nitro-1-naphthol Chemical Properties,Usage,Production

  • Uses KAT8-IN-1 is a lysine (K) acetyltransferase 8 (KAT8) inhibitor, with IC50s of 141 μM (KAT8), 221 μM (KAT2B), 106 μM (KAT3B), respectively. KAT8 inhibits histone acetyltransferases (HATs), and could result in disease states, such as cancer or inflammatory diseases[1].
  • Synthesis Reference(s) Journal of Medicinal Chemistry, 30, p. 906, 1987 DOI: 10.1021/jm00388a027
  • References [1] Wapenaar H, et al. The relevance of Ki?calculation for bi-substrate enzymes illustrated by kinetic evaluation of a novel lysine (K) acetyltransferase 8 inhibitor. Eur J Med Chem. 2017 Aug 18;136:480-486. DOI:10.1016/j.ejmech.2017.05.015
4-Nitro-1-naphthol Preparation Products And Raw materials
Raw materials
Preparation Products
Global(176)Suppliers
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  • Supplier:
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4-Nitro-1-naphthol Spectrum
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