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Boldenone

Description Sources

Boldenone

CAS No.846-48-0
Chemical Name:Boldenone
CBNumber:CB3364958
Molecular Formula:C19H26O2
Formula Weight:286.41
MOL File:846-48-0.mol

Boldenone Property

Melting point 164-166°C
alpha D25 +25° (in chloroform)
Boiling point 368.77°C (rough estimate)
Density 1.0655 (rough estimate)
refractive index 1.4709 (estimate)
storage temp. Controlled Substance, -20°C Freezer
solubility DMF: 25 mg/ml; DMSO: 15 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml
form A crystalline solid
pka 15.05±0.60(Predicted)
Water Solubility 57.1mg/L at 20℃
InChI InChI=1/C19H26O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h7,9,11,14-17,21H,3-6,8,10H2,1-2H3/t14-,15-,16-,17-,18-,19-/s3
InChIKey RSIHSRDYCUFFLA-KRHBYBJCNA-N
SMILES [C@@]12([H])CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@@]21[H])O |&1:0,10,12,16,18,21,r|
CAS DataBase Reference 846-48-0(CAS DataBase Reference)
FDA UNII 5H7I2IP58X
NIST Chemistry Reference Boldenone(846-48-0)

Safety

Hazard Codes :F,Xn
Risk Statements :11-20/21/22-36
Safety Statements :16-36/37
RTECS :BV7994400
HS Code :29372900

NFPA 704:

	0
2		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordDanger
Hazard statements H412-H362-H351-H360
Precautionary statements P201-P260-P263-P264-P270-P308+P313-P201-P202-P281-P308+P313-P405-P501-P273-P501

Boldenone Chemical Properties,Usage,Production

Description Boldenone is the chemical precursor of its endecylenate ester prodrug boldenone undecylenate – which is used extensively as a steroid for animals, mainly horses and cattle, under the brand name Equipoise, among others. For this application, it is injected to improve the weight, hair coat, appetite, and general physical condition of horses affected by disease, anorexia, or overwork. It is also used as an illegal doping agent for human athletes. As a derivative of testosterone, it retains its anabolic strength, but exhibits reduced androgenic effects.
Sources https://en.wikipedia.org/wiki/Boldenone_undecylenate
https://en.wikipedia.org/wiki/Boldenone
https://www.drugs.com/vet/equipoise.html
https://www.steroidal.com/steroid-profiles/equipoise/
https://www.evolutionary.org/equipoise-boldenone-undecylenate
Description Boldenone (Item No. 15432) is an analytical reference standard categorized as an anabolic androgenic steroid. Anabolic steroids, including boldenone, have been used to enhance physical performance in athletes. Boldenone is regulated as a Schedule III compound in the United States. This product is intended for research and forensic applications.
Chemical Properties Crystalline Solid
Uses Controlled substance. Anabolic steroid
Uses Boldenone is an anabolic steroid. Controlled substance.
Definition ChEBI: An 3-oxo-Delta1,Delta4-steroid substituted by an oxo group at position 3 and a beta-hydroxy group at position 17. It is an anabolic androgenic steroid that has been eveloped for veterinary use.
brand name Equipoise [Veterinary] (Fort Dodge Animal Health).
Synthesis Boldenone is obtained by reacting Testosterone with tert-butyldimethylsilyl chloride in the presence of DDQ.
Experimental Procedure: 29.0 g Testosterone was dissolved in 220 ml dioxan/THF 8:2 and cooled to 0°C on ice. After cooling down a solution of tert-butyldimethylsilyl chloride (46.0 g in 100 ml dioxan/THF 8:2) was added dropwise and stirred for 90 min at 0°C. Then a suspension of 32.0 g of DDQ in 200 ml dioxan/THF 8:2 was added in 4 equal portions over a period of 4 h. The reaction mixture was stirred for additional 12 h within coming from 0°C to room temperature. The resulting suspension was then filtered over Celite and rinsed with 300 ml THF. The filtrate was evaporated and brown oil was obtained. The oil was diluted in 1500 ml DCM and washed with 500 ml of 5% aqueous sodium hydroxide. The yellow organic phase was washed with 400 ml water and 400 ml saturated sodium chloride solution, before drying over magnesium sulfate. After evaporation, the crude product was chromatographed on silica gel by using hexane-ethyl acetate (3:7), followed by a recrystallization in ethyl acetate. 16.50 g of Boldenone was obtained as an amber solid (58%).