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2-Chloroethylamine hydrochloride

Chemical Properties Application

CAS No.870-24-6
Chemical Name:2-Chloroethylamine hydrochloride
CBNumber:CB3348187
Molecular Formula:C2H7Cl2N
Formula Weight:115.99
MOL File:870-24-6.mol

2-Chloroethylamine hydrochloride Property

Melting point 140-150 °C(lit.)
bulk density 750-850kg/m3
storage temp. Store below +30°C.
solubility 5666g/l
form Crystalline Powder
color White to light beige
PH 2-3 (5666g/l, H2O, 20℃)
Water Solubility SOLUBLE
Sensitive Hygroscopic
BRN 3590304
InChI InChI=1S/C2H6ClN.ClH/c3-1-2-4;/h1-2,4H2;1H
InChIKey ONRREFWJTRBDRA-UHFFFAOYSA-N
SMILES NCCCl.[H]Cl
CAS DataBase Reference 870-24-6(CAS DataBase Reference)
FDA UNII 8040U3I02T
EPA Substance Registry System 2-Chloroethylamine hydrochloride (870-24-6)
UNSPSC Code 12352107
NACRES NA.22

Safety

Hazard Codes :Xi,C
Risk Statements :36/37/38-68-34
Safety Statements :26-36-37/39-45-36/37/39
RIDADR :UN3261
WGK Germany :3
RTECS :KR1800000
F :3-10-34
TSCA :Yes
HazardClass :8
PackingGroup :III
HS Code :29211980
Toxicity :LD50 orally in Rabbit: > 2000 mg/kg

NFPA 704:

	0
2		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordDanger
Hazard statements H290-H314-H341
Precautionary statements P202-P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338

2-Chloroethylamine hydrochloride Price More Price(11)

Brand: Sigma-Aldrich(India)
Product number: C40200
Product name : 2-Chloroethylamine hydrochloride
Purity: 99%
Packaging: 5G
Price: ₹1948.5
Updated: 2022/06/14
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Brand: Sigma-Aldrich(India)
Product number: C40200
Product name : 2-Chloroethylamine hydrochloride
Purity: 99%
Packaging: 100G
Price: ₹3182.55
Updated: 2022/06/14
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Brand: Sigma-Aldrich(India)
Product number: 8.20265
Product name : 2-Chloroethylammonium chloride
Purity: for synthesis
Packaging: 100G
Price: ₹3300
Updated: 2022/06/14
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Brand: Sigma-Aldrich(India)
Product number: 8.20265
Product name : 2-Chloroethylammonium chloride
Purity: for synthesis
Packaging: 250G
Price: ₹5590
Updated: 2022/06/14
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Brand: Sigma-Aldrich(India)
Product number: 23035
Product name : 2-Chloroethylamine hydrochloride
Purity: purum, ≥98.0% (AT)
Packaging: 5G
Price: ₹2478.93
Updated: 2022/06/14
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2-Chloroethylamine hydrochloride Chemical Properties,Usage,Production

Chemical Properties
2-Chloroethylamine hydrochloride (C2H7Cl2N, CAS registry No. 870-24-6) is a white to light beige crystalline powder. It is soluble in water and stable at room temperature in closed containers under normal storage and handling conditions. It should store in a tightly closed container, in a cool, dry, well-ventilated area away from incompatible substances and should be protected from moisture.
Application
2-Chloroethylamine hydrochloride is an important fine chemical intermediate. It can be used for the synthesis of fluvoxamine maleate, which is an important antidepressant drug. 2-Chloroethylamine hydrochloride can also be used as the substrate to synthesize 2-(2'-Aminoaryl)oxazolines and their derivatives, which have been studied as ligands for a variety of metal chelates and are known to possess biological activity in both free ligand and chelated forms. Meanwhile, 2-chloroethylamine hydrochloride can be used for chemical modification of chitosan to improve the biological activity of chitosan.
2-Chloroethylamine hydrochloride can also react with hydroxypropyl starch (HPS) to form aminoethyl hydroxypropyl starch (AEHPS), which can react with collagen peptide (COP) by using microbial transglutaminase (MTGase) as biocatalyst to synthesize aminoethyl hydroxypropyl starch collagen peptide (AEHPS-COP). The AEHPS-COP showed a promising potential application in cosmetic, biomedical and pharmaceutical fields with improved in vitro antioxidant activities.
Chemical Properties WHITE TO LIGHT BEIGE CRYSTALLINE POWDER
Uses 2-Chloroethylamine hydrochloride can be used in the preparation of novel Schiff base ligands. These ligands, when immobilized on silica gels, form inexpensive materials for the removal of metal ions such as Ni²⁺ and Co²⁺ ions from contaminated water.
Other applications:
- Alginate derivatization via aminoethylation to form aminoethyl alginate.
- Synthesis of N-(2-chloroethyl)-benzaldimine.
- Derivatization of starch to form aminoethyl (AE-St) starch derivatives.
Uses 2-chloroethylamine hydrochloride is used as an intermediate in active pharmaceutical ingredients and dyes. It is also used in organic synthesis. Further, it is employed as a derivatizing reagent for amino acids, dipeptides and nucleotides.