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Propargyl-PEG6-NHS ester

Propargyl-PEG6-NHS ester Structure
Propargyl-PEG6-NHS ester
  • CAS No.2093153-99-0
  • Chemical Name:Propargyl-PEG6-NHS ester
  • CBNumber:CB33373762
  • Molecular Formula:C20H31NO10
  • Formula Weight:445.46
  • MOL File:2093153-99-0.mol
Propargyl-PEG6-NHS ester Property
  • Boiling point 530.8±60.0 °C(Predicted)
  • Density 1.22±0.1 g/cm3(Predicted)
  • solubility Soluble in DMSO, DCM
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

Propargyl-PEG6-NHS ester Chemical Properties,Usage,Production

  • Description Propargyl-PEG6-NHS ester is an amine reactive linker. The alkyne in this linker can react with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry reaction. The PEG spacer increases solubility of the molecule in aqueous media.
  • Uses Propargyl-PEG6-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG6-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • IC 50 Cleavable Linker; PEGs; Alkyl/ether
  • References [1] Anandan Palani, et al. Insulin-incretin conjugates. WO2017160669A1.
Propargyl-PEG6-NHS ester Preparation Products And Raw materials
Raw materials
Preparation Products
Propargyl-PEG6-NHS ester Suppliers
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Propargyl-PEG6-NHS ester Spectrum
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