ChemicalBook > CAS DataBase List > PF-5190457
PF-5190457
PF-5190457
- CAS No.1334782-79-4
- Chemical Name:PF-5190457
- CBNumber:CB33303958
- Molecular Formula:C29H32N6OS
- Formula Weight:512.67
- MOL File:1334782-79-4.mol
PF-5190457 Property
- Density 1.41±0.1 g/cm3(Predicted)
- storage temp. room temp
- solubility DMSO: 250 mg/mL (487.64 mM)
- form powder
- pka 8.38±0.20(Predicted)
- color white to beige
- optical activity [α]/D +45 to +55°, c = 0.5 in methanol
- FDA UNII FF33NL9U5G
- UNSPSC Code 51111800
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H315-H319
- Precautionary statements P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
PF-5190457 Price
More Price(2)
- Brand: Sigma-Aldrich(India)
- Product number: PZ0270
- Product name : PF-05190457
- Purity: ≥95% (HPLC)
- Packaging: 5MG
- Price: ₹10825
- Updated: 2022/06/14
- Buy: Buy
- Brand: Sigma-Aldrich(India)
- Product number: PZ0270
- Product name : PF-05190457
- Purity: ≥95% (HPLC)
- Packaging: 25MG
- Price: ₹43613.93
- Updated: 2022/06/14
- Buy: Buy
PF-5190457 Chemical Properties,Usage,Production
- Uses PF 5190457 is a potent, selective, and orally bioavailable ghrelin receptor inverse agonist.
- Biochem/physiol Actions PF-05190457 is an orally available, potent and selective ghrelin receptor inverse agonist. PF-05190457 potently increases insulin secretion in glucose-stimulated human islets.
-
in vivo
PF-5190457 has excellent selectivity and demonstrates robust increases in glucose-stimulated insulin secretion in human whole and dispersed islets[1].
- storage Store at -20°C
PF-5190457 Preparation Products And Raw materials
Raw materials
Preparation Products
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- 抑制剂
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- 化合物PF-5190457,10 MM DMSO 溶液
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- 化合物PF-5190457
- 1334782-79-4
- PF-5190457, 10 mM in DMSO
- (R)-2-(2-Methylimidazo[2,1-b]thiazol-6-yl)-1-(2-(5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonan-7-yl)ethan-1-one
- (R)-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-1-(2-(5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonan-7-yl)ethanone
- Ethanone, 1-[2-[(1R)-2,3-dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-
- PF 5190457,Growth hormone secretagogue receptor,PF 05190457,PF-5190457,PF5190457,GHSR,Inhibitor,PF05190457,inhibit
- PF-05190457
- PF-05190457 >=95% (HPLC)
- 1-[2-[(1R)-2,3-Dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3,5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)ethanone
- PF-5190457