ChemicalBook > CAS DataBase List > Tr-PEG6
Tr-PEG6
Tr-PEG6
- CAS No.141282-24-8
- Chemical Name:Tr-PEG6
- CBNumber:CB33303332
- Molecular Formula:C29H36O6
- Formula Weight:480.59
- MOL File:141282-24-8.mol
Tr-PEG6 Property
- Boiling point 595.6±45.0 °C(Predicted)
- Density 1.125±0.06 g/cm3(Predicted)
- pka 14.36±0.10(Predicted)
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
Tr-PEG6 Chemical Properties,Usage,Production
- Description Tr-PEG6 is a trityl ether protected PEG chain. The trityl ether can be removed under mildly acidic conditions or via hydrogenolysis. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.
- Uses Tr-PEG5-OH is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Tr-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
- IC 50 Non-cleavable Linker; PEGs
-
References
[1] Branderhorst HM, et al. Strong inhibition of cholera toxin binding by galactose dendrimers. Chem Commun (Camb). 2007 Dec 21;(47):5043-5. DOI:10.1039/b711070g
[2] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005
Tr-PEG6 Preparation Products And Raw materials
Raw materials
Preparation Products
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141282-24-8, Tr-PEG6Related Search:
- 五甘醇单三苯甲基醚
- 141282-24-8
- Trt-PEG5-OH
- 3,6,9,12,15-Pentaoxahexadecan-1-ol, 16,16,16-triphenyl-
- 2-[2-[2-[2-(2-trityloxyethoxy)ethoxy]ethoxy]ethoxy]ethanol
- Tr-PEG5-OH
- Tr-PEG6