ChemicalBook > CAS DataBase List > Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate

Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate

Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate Property

Boiling point 349.0±44.0 °C(Predicted)
Density 1.23
vapor pressure 0.008Pa at 25℃
pka 11.63±0.10(Predicted)
InChI InChI=1S/C11H13ClN2O3/c1-3-17-11(15)10(12)14-13-8-4-6-9(16-2)7-5-8/h4-7,13H,3H2,1-2H3/b14-10-
InChIKey ATNPZEGMKLGIFA-UVTDQMKNSA-N
SMILES C(OCC)(=O)/C(/Cl)=N/NC1=CC=C(OC)C=C1
LogP 2.53

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordDanger
Hazard statements H301-H311-H331-H341
Precautionary statements P201-P202-P261-P264-P270-P271-P280-P302+P352-P304+P340-P308+P313-P310-P330-P361-P403+P233-P405-P501

Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate Chemical Properties,Usage,Production

Uses Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development and chemical and pharmaceutical production processes.
Synthesis
Preparation of ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate To p-anisidine (16 g, 0.129 mol) in conc. HCL (40 mL), 100 mL) H2O, cooled to -5?? C. and sodium nitrite (9.4 g, 0.136 mol) in H2O (60 mL) was added. The reaction mixture was stirred at -5?? C. for 20 min and a mixture of ethylchloroacetoacetate (22 g, 0.133 mol), ethanol (100 mL), sodiumacetate (32 g, 0.389 mmol), and H2O (400 mL) was added. The reaction was allowed to warm up to room temperature and stirred for 2h. The product precipitated as a black solid. It was filtered and dried (30 g). 1H-NMR (CDCl3) |? 8.28 (s, 1H), 7.18 (d, 2H), 6.90 (d, 2H), 4.41 (q, 2H), 3.80 (s, 3H), 1.42 (t, 3H) ppm.

Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate Preparation Products And Raw materials

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Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate Spectrum

473927-63-8, Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoateRelated Search:

473927-63-8
化工中间体
医用原料
化学试剂
医药原料药
有机原料
柏锦生物
原料药
杂质对照品
(2Z)-2-氯-2-[2-(4-甲氧基苯基)肼亚基]乙酸乙酯
2-氯-2-(2-(4-甲氧基苯基)腙基)乙酸乙酯
阿皮沙班杂质O
阿哌沙班杂质APX-YJZ
阿哌沙班杂质O
(2Z)-氯[(4-甲氧基苯基)亚肼基]乙酸乙酯(阿哌沙班中间体) 1KG
(2Z)-氯[(4-甲氧基苯基)亚肼基]乙酸乙酯
(2Z)-氯[(4-甲氧基苯基)亚肼基]乙酸乙酯(阿哌沙班中间体)
473927-63-8
(2Z)-Chloro[(4-methoxyphenyl)hydrazono]aceticacidethylester
Ethyl(2Z)-2-chloro-2-((4-methoxyphenyl)hydrazono)acetate
Ethyl (2Z)-2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene]acetate
Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetateQ: What is Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate Q: What is the CAS Number of Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate
Acetic acid, chloro[(4-methoxyphenyl)hydrazono]-, ethyl este...
Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene]-, ethyl ester, (2Z)-
Apixaban int
Apixaban Impurity O
ethyl (2Z)-2-chloro-2-[2-(4-methoxyphenyl)hydrazin-1-ylidene]acetate
Apixaban I
Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]acetate
(2Z)-2-Chloro-2-[2-(4-methoxyphenyl)hydrazinylidene]acetic acid ethyl ester
Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate
Acetic acid, chloro[(4-Methoxyphenyl)hydrazono]-, ethyl ester, (2Z)-