ChemicalBook > CAS DataBase List > 4-[Tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-hydroxymethylfuran-2-yl]-1,2-benzenediol

4-[Tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-hydroxymethylfuran-2-yl]-1,2-benzenediol

4-[Tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-hydroxymethylfuran-2-yl]-1,2-benzenediol Structure
4-[Tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-hydroxymethylfuran-2-yl]-1,2-benzenediol
  • CAS No.40951-69-7
  • Chemical Name:4-[Tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-hydroxymethylfuran-2-yl]-1,2-benzenediol
  • CBNumber:CB32277524
  • Molecular Formula:C19H22O6
  • Formula Weight:346.37
  • MOL File:40951-69-7.mol
4-[Tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-hydroxymethylfuran-2-yl]-1,2-benzenediol Property
  • Melting point 157-158 °C(Solv: methanol (67-56-1))
  • Boiling point 590.3±50.0 °C(Predicted)
  • Density 1.331±0.06 g/cm3(Predicted)
  • pka 9.60±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

4-[Tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-hydroxymethylfuran-2-yl]-1,2-benzenediol Chemical Properties,Usage,Production

  • Uses Taxiresinol is an orally active and potent lignan, that can be isolated from the heartwood of Taxus baccata. Taxiresinol shows significant antinociceptive activity[1].
  • in vivo

    Taxiresinol (100 mg/kg, oral administration, once) shows significant antinociceptive activity against p-benzoquinone-induced abdominal contractions in mice[1].

    Animal Model:Male Swiss albino mice (20-25 g)[1]
    Dosage:100 mg/kg
    Administration:Oral administration, sixty minutes after the oral administration of test sample, the mice were intraperitoneally injected with 0.1 ml/10 g body weight of 2.5% (v/v) p-benzoquinone solution in distilled H2O.
    Result:Showed significant antinociceptive activity against p-benzoquinone-induced abdominal contractions (writhing movements) in mice, with a inhibitory ratio of 37.8%.
  • References [1] Küpeli E, et al. Anti-inflammatory and antinociceptive activity of taxoids and lignans from the heartwood of Taxus baccata L. J Ethnopharmacol. 2003 Dec;89(2-3):265-70. DOI:10.1071/bi9760365
4-[Tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-hydroxymethylfuran-2-yl]-1,2-benzenediol Preparation Products And Raw materials
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4-[Tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-hydroxymethylfuran-2-yl]-1,2-benzenediol Suppliers
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4-[Tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-hydroxymethylfuran-2-yl]-1,2-benzenediol Spectrum
40951-69-7, 4-[Tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-hydroxymethylfuran-2-yl]-1,2-benzenediolRelated Search:
  • 标准品 -中药标准品
  • 木脂素
  • 分析试剂标准品
  • 化合物 TMA0627
  • 紫杉脂素
  • 40951-69-7
  • 1,2-Benzenediol, 4-[(2S,3R,4R)-tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-(hydroxymethyl)-2-furanyl]-
  • Taxiresinol
  • 4-[Tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-hydroxymethylfuran-2-yl]-1,2-benzenediol

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