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methyl orsellinate

methyl orsellinate Structure
methyl orsellinate
  • CAS No.3187-58-4
  • Chemical Name:methyl orsellinate
  • CBNumber:CB31484897
  • Molecular Formula:C9H10O4
  • Formula Weight:182.17
  • MOL File:3187-58-4.mol
methyl orsellinate Property
  • Melting point 141-142℃
  • Boiling point 339℃
  • Density 1.296
  • Flash point 138℃
  • storage temp. 2-8°C
  • solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
  • form Solid
  • pka 8.27±0.23(Predicted)
  • color White to Off-White
  • InChI InChI=1S/C9H10O4/c1-5-3-6(10)4-7(11)8(5)9(12)13-2/h3-4,10-11H,1-2H3
  • InChIKey NCCWCZLEACWJIN-UHFFFAOYSA-N
  • SMILES C(OC)(=O)C1=C(C)C=C(O)C=C1O
  • LogP 2.380 (est)
  • EPA Substance Registry System Benzoic acid, 2,4-dihydroxy-6-methyl-, methyl ester (3187-58-4)
Safety
  • HS Code  :2918290090
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

methyl orsellinate Chemical Properties,Usage,Production

  • Uses Methyl 2,4-Dihydroxy-6-methylbenzoate (methyl orsellinate) is a useful synthetic intermediate in the synthesis of Grifolic Acid (G786500); a selective partial GPR120 agonist. Grifolic Acid induces ERK and [Ca2+]i responses in cells expressing GPR120, but has no effects on those expressing GPR40.
  • Definition ChEBI: Orsellinic acid methyl ester is a hydroxybenzoic acid. It has a role as a metabolite.
  • Biochem/physiol Actions Methyl orsellinate, an antifungal compound, is produced during submerged culture from Sparassis crispa. Methyl orsellinate have appeared to have higher antifungal activity than sparassol. Methyl orsellinate is a phytotoxic compound; it can cause significant inhibition of radicle growth of Amaranthus hypochondriacus and Echinochloa crus-galli, interact with bovine-brain calmodulin and inhibit the activation of the calmodulin-dependent enzyme cAMP phosphodiesterase. It could inhibit PTP1B activity with 50% inhibitory concentration values of 277 +/- 8.6 microM; the selective inhibition of PTP1B has been widely recognized as a potential drug target for the treatment of type 2 diabetes and obesity; methyl orsellinate may treat the type 2 diabetes and obesity.
methyl orsellinate Preparation Products And Raw materials
Raw materials
Preparation Products
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methyl orsellinate Spectrum
3187-58-4, methyl orsellinateRelated Search:
  • Aromatic Esters
  • 其它酚类
  • 甲基 2,4-二羟基-6-甲基苯甲酸酯
  • 苔色酸甲酯
  • 3187-58-4
  • Methyl
  • METHYL ORSELLINATE
  • 6-Methyl-β-resorcylicacidmethyl
  • BENZOIC ACID,2,4-DIHYDROXY-6-METHYL-, METHYL ESTER
  • o-Orsellinic acid methyl
  • Methyl o-orsellinate
  • 6-Methyl-β-resorcylic acid methyl
  • Orsellinic acid methyl

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