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Sultopride

Sultopride Structure
Sultopride
  • CAS No.53583-79-2
  • Chemical Name:Sultopride
  • CBNumber:CB2875390
  • Molecular Formula:C17H26N2O4S
  • Formula Weight:354.468
  • MOL File:53583-79-2.mol
Sultopride Property
  • Melting point 181-182 °C
  • Boiling point 530.0±50.0 °C(Predicted)
  • Density 1.1814 (rough estimate)
  • refractive index 1.6930 (estimate)
  • storage temp. Store at -20°C
  • solubility Soluble in DMSO
  • pka 13.99±0.46(Predicted)
  • FDA UNII AA0G3TW31W
  • ATC code N05AL02
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H335
  • Precautionary statements P261-P305+P351+P338

Sultopride Chemical Properties,Usage,Production

  • Originator Barnetil,Delagrange,France,1976
  • Definition ChEBI: Sultopride is a member of salicylamides.
  • Manufacturing Process A solution of 17.22 g of N-ethyl-α-aminomethylpyrrolidine in 360 ml of pyridine is placed in a 1 l balloon flask. A solution of 3.51 g of phosphorus trichloride in 40 ml of pyridine is added at ambient temperature. After the mixture has been stirred for 1 hour, 10 g of 2-methoxy-5-ethylsulfonylbenzoic acid is introduced. The mixture is heated under reflux for 4 ? hours. After cooling, the solvent is evaporated under vacuum and the residue is dissolved in 200 ml of 20% sodium hydroxide. The solution is extracted with 200 ml of chloroform.
    The organic solution is dried and filtered and the solvent is evaporated under vacuum; the residue is dissolved in 150 ml of ethanol and the solution is acidified with hydrochloric acid. The hydrochloride is dried without heating and recrystallized from 100 ml of absolute ethanol. 7.2 g of N-(1-ethyl-2- pyrrolidyl-methyl-2-methoxy-5-ethylsulfonylbenzamide hydrochloride is produced. Melting point: 190°C to 193°C.
  • brand name Banotil;Barnotil;Topral.
  • Therapeutic Function Neuroleptic
Sultopride Preparation Products And Raw materials
Raw materials
Preparation Products
Sultopride Suppliers
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Sultopride Spectrum
53583-79-2, SultoprideRelated Search:
  • 抑制剂
  • 化合物 T7180L
  • 舒托必利
  • 舒多必利
  • 吡乙磺苯酰胺
  • 53583-79-2
  • 4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxybenzamid
  • Sultopridum
  • Benzamide, N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxy-
  • N-[(1-Ethylpyrrolidin-2-yl)methyl]-5-(ethylsulfonyl)-2-(methyloxy)benzamide
  • N-[(1-Ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide
  • LIN 1418
  • Benzamide, N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxy- (9CI)
  • Barnetil
  • Sultopride

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