ChemicalBook > CAS DataBase List > cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate

cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate

cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate Structure
cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate
  • CAS No.134071-44-6
  • Chemical Name:cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate
  • CBNumber:CB2855192
  • Molecular Formula:C21H20Cl2N2O5S
  • Formula Weight:483.36
  • MOL File:134071-44-6.mol
cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate Property
  • Melting point 120-122°C
  • Boiling point 665.7±55.0 °C(Predicted)
  • Density 1.44±0.1 g/cm3(Predicted)
  • storage temp. Inert atmosphere,Room Temperature
  • solubility DMSO (Slightly), Methanol (Slightly)
  • pka 6.88±0.12(Predicted)
  • form Solid
  • color White to Off-White
  • CAS DataBase Reference 134071-44-6(CAS DataBase Reference)
  • FDA UNII 644X337Z6T
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate Chemical Properties,Usage,Production

  • Chemical Properties Off-White Solid
  • Uses cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl p-Tolylsulfonate (Ketoconazole EP Impurity E) is an intermediate in the synthesis of the drug Ketoconazole (K186000).
cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate Preparation Products And Raw materials
Raw materials
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cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate Spectrum
134071-44-6, cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonateRelated Search:
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  • 中间体
  • C21H20Cl2N2O5S
  • 124071-44-6
  • 酮康唑中间体1E
  • 酮康唑杂杂质E
  • 酮康唑中间体,酮康唑活性酯(134071-44-6)
  • 顺式-[2-(2,4-二氯苯基)-2-(1H-咪唑-1-基甲基)-1,3-二氧戊环-4-基]甲醇对甲苯磺酸酯,酮康唑活性酯
  • 酮康唑中间体,酮康唑活性酯
  • 酮康唑中间体/活性酯
  • 3- [2-(2,4-二氯苯基)-2-(1,2,4-三唑-1-基甲基)-1,3-二氧戊环-4-基] -2,4-二甲基苯磺酸盐
  • 酮康唑杂质E(EP)
  • KETOCONAZOLE 杂质E
  • 酮康唑杂质E(EP/BP)
  • 酮康唑EP杂质E
  • 活性酯 (酮康唑中间体)
  • 酮康唑杂质E
  • 酮康唑中间体
  • 顺式-[2-(2,4-二氯苯基)-2-(1H-咪唑-1-基甲基)-1,3-二氧戊环-4-基]甲醇对甲苯磺酸酯
  • 活性酯 (酮康唑)
  • 134071-44-6
  • (2RS,4SR)-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl 4-Methylbenzen
  • [(2R,4R)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl 4-methylbenzenesulfonate
  • (cis-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-methylbenzenesul
  • Ketoconazole Intermediate 1e
  • CIS-[2-2,4-DICHLOROPHENYL-2-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4YL]METHYL-4-METHYLBENZENESULPHONATE(Cis Tosylate)
  • Cis-(2-(2,4-Dichlorophenyl)-2-(lH- Imidazot-1- yl-Methyl)-1,3- Dioxolan-4-yl}methyl-4-Methanol
  • KETOCOZOLE EP IMPURITY E
  • Active Ester
  • CIS-TOSYLATE
  • [(2RS,4SR)-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl 4-methylbenzenesulfonate
  • K6 / Cis Tosylate
  • cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-d...
  • Cis - (2 - (2, 4 - dichlorobenzene) - 2 - (1 h - imidazole 1 - methyl) - 1, 3 - dioxolane - 4 - base) methanol p-toluene sulfonic acid ester
  • ACTIVE ESTER OF KETOCONZOL
  • CIS TOSYLATE : Cis-2-(2,4-Dichlorophenyl)-2-(1H-Imidazole-1-yl)Methyl)-4-(p-Toluene Sulfonyloxy)methyl-1,3-Dioxalane)
  • [(2RS,4SR)-2-(2,4-Dichlorophenyl)-2
  • Cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate (134071-44-6)
  • CIS-2-(2 4- DICHLOROPHENYL)-2-(1-H-IMIDA ZOLE-YL-METHYL) -1 3-DIOXOLAN-4-YL] METH YL-4-METHYLBENZENESULPHONATE
  • 2-[[2-(2,4-dichlorophenyl)-2-(1-imidazolylmethyl)-1,3-dioxolan-4-yl]methyl]-4-methylbenzenesulfonate
  • Ketoconazole Impurity 5（Ketoconazole EP Impurity E）
  • Cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-l-ylmethyl)- 1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate (CisTosylate)
  • Ketoconazole EP Impurity E
  • (cis-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-methylbenzene
  • CIS-[2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXALAN-4-YL]METHYL-P-TOLYSULFONATE

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