Chemical Properties
| form | Liquid |
| color | Colorless to light yellow |
Lacnotuzumab Chemical Properties,Usage,Production
Uses
Lacnotuzumab (MCS110) is a neutralizing humanized IgG1/κ monoclonal antibody targeting CSF-1 that prevents CSF-1 from activating the CSF-1R. Lacnotuzumab can be used for the research of pigmented villonodular synovitis[1][2].in vivo
Lacnotuzumab neutralizes recombinant and serum-derived forms of cynomolgus CSF-1, but it does not recognize rodent or rabbit CSF-1[2].
References
[1] Kuemmel S, et, al. A Randomized Phase II Study of Anti-CSF1 Monoclonal Antibody Lacnotuzumab (MCS110) Combined with Gemcitabine and Carboplatin in Advanced Triple-Negative Breast Cancer. Clin Cancer Res. 2022 Jan 1;28(1):106-115. DOI:10.1158/1078-0432.CCR-20-3955[2] Pognan F, et, al. Colony-Stimulating Factor-1 Antibody Lacnotuzumab in a Phase 1 Healthy Volunteer Study and Mechanistic Investigation of Safety Outcomes. J Pharmacol Exp Ther. 2019 Jun;369(3):428-442. DOI:10.1124/jpet.118.254128
Lacnotuzumab Suppliers
Global(18)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| tp@aladdinsci.com | 54731 | 58 | |||
| 6206333 13167063860 | anhua.mao@aladdin-e.com | 49544 | 58 | ||
| 17316404525 17316404525 | 209533805@qq.com | 9790 | 58 | ||
| 15817493340 | 981810490@qq.com | 1577 | 58 | ||
| 021-65675885 18964387627 | customer_service@efebio.com | 11963 | 58 | ||
| 0573-83568680 18057391398 | 3956524501@qq.com | 1441 | 58 | ||
| 027-87008169 17762441161 | info@atagenix.com | 9997 | 58 | ||
| 18916372613 | yanzihan@shyuanye.com | 87240 | 60 | ||
| 4008200310 15002144251 | marketing@tsbiochem.com | 24951 | 58 | ||
| 18007167883 18007167883 | Service@mabnus.com | 921 | 58 |