ChemicalBook > CAS DataBase List > HYPOCRELLIN A
HYPOCRELLIN A
HYPOCRELLIN A
- CAS No.77029-83-5
- Chemical Name:HYPOCRELLIN A
- CBNumber:CB2772800
- Molecular Formula:C30H26O10
- Formula Weight:546.52
- MOL File:77029-83-5.mol
HYPOCRELLIN A Property
- Melting point 209-210 °C
- Boiling point 922.8±65.0 °C(Predicted)
- Density 1.55±0.1 g/cm3(Predicted)
- storage temp. 2-8°C
- solubility DMF: 2mg/mL; DMSO: 3mg/mL; Ethanol: 0.3mg/mL
- form A solid
- pka 7.03±0.60(Predicted)
- color Brown to red
- FDA UNII V86371B0XS
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H315-H319
- Precautionary statements P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
HYPOCRELLIN A Chemical Properties,Usage,Production
- Uses Hypocrellin A is an antimicrobial and antileishmanial activity. Ga(3+)-Hypocrellin interacts with myoglobin in vitro.
-
in vivo
Hypocrellin A (2.5 and 5 mg/kg; i.p.; once every two days for fourteen days) inhibits tumor growth in a non-small cell lung cancer xenograft model mouse model[8].
Animal Model: H460 cells were inoculated subcutaneously on the backs of BALB/c nude mice[8] Dosage: 2.5 and 5 mg/kg Administration: i.p.; Inject once every two days for fourteen days Result: Induced the expression of the pro-apoptotic protein BAX and inhibited the expression of the anti-apoptotic protein BCL-2 in NSCLC tumors. - IC 50 Leishmania
HYPOCRELLIN A Preparation Products And Raw materials
Raw materials
Preparation Products
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77029-83-5, HYPOCRELLIN ARelated Search:
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- 蒽醌类
- 化学品
- 抑制剂
- 药靶配体
- 蒽醌
- 通用生化试剂-天然产物
- 标准品,对照品
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- C30H26O10
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- (1S,2R)-1-acetyl-2,5,12-trihydroxy-4,8,9,13-tetramethoxy-2-m...
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- (1S,2R)-1-acetyl-2,5,12-trihydroxy-4,8,9,13-tetramethoxy-2-methyl-2,3-dihydro-1H-cyclohepta[ghi]perylene-6,11-dione
- 1H-Cyclohepta[ghi]perylene-5,12-dione,1-acetyl-2,3-dihydro-2,6,11-trihydroxy-4,8,9,13-tetramethoxy-2-methyl-,stereoisomer
- HYPOCRELLIN A
- HYPOCRELLIN