ChemicalBook > CAS DataBase List > 5-Nitrofurfural

5-Nitrofurfural

CAS No.698-63-5
Chemical Name:5-Nitrofurfural
CBNumber:CB2711562
Molecular Formula:C5H3NO4
Formula Weight:141.08
MOL File:698-63-5.mol

5-Nitrofurfural Property

Melting point 37-39 °C(lit.)
Boiling point 121 °C10 mm Hg(lit.)
Density 1.349 g/mL at 25 °C(lit.)
refractive index n20/D 1.59(lit.)
Flash point 92 °F
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
form Crystalline Low Melting Solid
color Yellow to brown
Water Solubility sparingly soluble
Sensitive Air & Light Sensitive
BRN 120539
InChIKey SXINBFXPADXIEY-UHFFFAOYSA-N
CAS DataBase Reference 698-63-5(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII XXX18AU0Z3
NIST Chemistry Reference 2-Furancarboxaldehyde, 5-nitro-(698-63-5)
UNSPSC Code 12352100
NACRES NA.22

Safety

Hazard Codes :F,Xi,Xn
Risk Statements :11-68-10
Safety Statements :16-36/37
RIDADR :UN 1325 4.1/PG 2
WGK Germany :3
RTECS :LT7200000
Hazard Note :Irritant
HazardClass :3.2
PackingGroup :III
HS Code :29321900
Hazardous Substances Data :698-63-5(Hazardous Substances Data)

NFPA 704:

	3
1		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordDanger
Hazard statements H228
Precautionary statements P210

5-Nitrofurfural Price More Price(4)

Brand: Sigma-Aldrich(India)
Product number: 170968
Product name : 5-Nitro-2-furaldehyde
Purity: 99%
Packaging: 5G
Price: ₹2933.58
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 170968
Product name : 5-Nitro-2-furaldehyde
Purity: 99%
Packaging: 25G
Price: ₹10640.98
Updated: 2022/06/14
Buy: Buy

Brand: TCI Chemicals (India)
Product number: N0387
Product name : 5-Nitro-2-furaldehyde
Purity: min. 98.0 %
Packaging: 5G
Price: ₹3100
Updated: 2022/05/26
Buy: Buy

Brand: TCI Chemicals (India)
Product number: N0387
Product name : 5-Nitro-2-furaldehyde
Purity: min. 98.0 %
Packaging: 25G
Price: ₹7000
Updated: 2022/05/26
Buy: Buy

5-Nitrofurfural Chemical Properties,Usage,Production

Description Nitrofuran carboxaldehyde (NFC) is used to synthesize many drugs and chemicals such as nifuraldezone, puraguanidine, nifuratrone, furmethoxadone, etc. Furfural the main structure of NFC was determined many years ago to be a byproduct of formic acid synthesis. Furfural is produced from agricultural byproducts such as sugarcane bagasse and corncobs.
Chemical Properties Yellow to brown crystalline low melting solid
Uses NFC and its derivatives have antibacterial and antifungal activities. They destroy both gram-positive and gram-negative organisms such as Staphylococcus aureus, Salmonella schotmuelleri, Pseudomonas aeruginosa, Proteus vulgaris, Escherichia coli, and Streptococcus pyogenes. They may be used as antibacterial agents in a prophylactic manner, for example, in cleaning and disinfecting products. This compound also has antitrichomonal and antifungal activities.
Uses 5-Nitro-2-furaldehyde was used in the synthesis of a series of 4-(5-nitrofuran-2-yl)prop-2-en-1-one derivatives. . It was also used in the synthesis of modified mesoporous silica (MCM-41). 5-Nitrofurfural can be commonly used as pharmaceutical intermediates.
Definition ChEBI: 5-Nitrofurfural is a C-nitro compound and a member of furans.
Production Methods Furfural is nitrated in acetic anhydride solution at 25 – 40 ℃ to give the diacetate [92-55-7], which is purified by recrystallization from isopropanol and then used directly for the production of derived drugs.
Toxicity evaluation NFC inhibits the uptake of oxygen and disrupts cellular respiration within mitochondria. NFC and other nitrofurans are relatively potent inhibitors of monoamine oxidase enzyme in mammalian and avian species.