Mal-PEG1-NHS ester

Description Mal-PEG1-NHS ester is a PEG linker containing a maleimide group and an NHS ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
Biological Activity Mal-PEG1-NHS ester is a cleavable PEG-based ADC linker for the synthesis of antibody drug conjugates (ADCs). It is a PEG-based PROTAC linker that can be used to synthesize PROTACs.
in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

target

Mal-PEG1-NHS ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Mal-PEG1-NHS ester Spectrum

1807518-72-4, Mal-PEG1-NHS esterRelated Search:

peg
抑制剂
PEG系列产品-Mal-PEG系列
生物医学材料
助剂
马来酰亚胺-一聚乙二醇-丙烯酸琥珀酰亚胺酯/1807518-72-4
MAL-PEG1-NHS酯
2,5-二氧代吡咯烷-1-基3-(2-(2,5-二氧代-2,5-二氢-1H-吡咯-1-基)乙氧基)丙酸酯
丙酸琥珀酰亚胺酯-乙二醇-马来酰亚胺
化合物MAL-PEG1-NHS ESTER
马来酰亚胺-PEG1-琥珀酰亚胺酯
马来酰亚胺-聚乙二醇-琥珀酰亚胺酯
3-(2-(2,5-二氧代-2,5-二氢-1H-吡咯-1-基)乙氧基) 2,5-二氧代吡咯烷-1-基丙酸酯
马来酰亚胺-聚乙二醇-NHS 酯
马来酰亚胺-一聚乙二醇-丙烯酸琥珀酰亚胺酯
1807518-72-4
Mal-PEG1-CH2CH2COONHS
PROTAC,Antibody-drug conjugates linkers,Inhibitor,inhibit,PROTAC Linkers,Mal-PEG-1-NHS ester,PEG,Linker,ADC Linkers,Mal PEG1 NHS ester,ADC,MalPEG1NHS ester
Mal-PEG1-SPA
Propanoic acid, 3-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester
CAS_1807518-72-4
2,5-Dioxopyrrolidin-1-yl 3-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)propanoate
Mal-PEG1-NHS ester

Cleavable

PEGs

Mal-PEG1-NHS ester Chemical Properties,Usage,Production