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OSI-420

OSI-420 Structure
OSI-420
  • CAS No.183320-51-6
  • Chemical Name:OSI-420
  • CBNumber:CB22561488
  • Molecular Formula:C21H22ClN3O4
  • Formula Weight:415.87
  • MOL File:183320-51-6.mol
OSI-420 Property
  • storage temp. Store at -20°C
  • solubility DMSO : 50 mg/mL (120.23 mM; Need ultrasonic)
  • form Powder
  • color White to off-white
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

OSI-420 Chemical Properties,Usage,Production

  • Uses OSI 420 can be used in biological study of effects of cytochrome P 450 3A on pharmacokinetic interaction between erlotinib and docetaxel in rats.
  • Uses OSI-420 (Desmethyl Erlotinib,CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells.
  • target EGFR
OSI-420 Preparation Products And Raw materials
Raw materials
Preparation Products
OSI-420 Suppliers
Global(109)Suppliers
  • Supplier：
    Standardpharm Co. Ltd.
  • Tel：86-714-3992388
  • Email：overseasales1@yongstandards.com
  • Country：United States
  • ProdList：14332
  • Advantage：58
  • Supplier：
    BOC Sciences
  • Tel：+1-631-485-4226
  • Email：inquiry@bocsci.com
  • Country：United States
  • ProdList：19552
  • Advantage：58
  • Supplier：
    career henan chemical co
  • Tel：+86-0371-86658258<br/>+8613203830695
  • Email：factory@coreychem.com
  • Country：China
  • ProdList：29808
  • Advantage：58
  • Supplier：
    TargetMol Chemicals Inc.
  • Tel：+1-781-999-5354<br/>+1-00000000000
  • Email：marketing@targetmol.com
  • Country：United States
  • ProdList：32159
  • Advantage：58
  • Supplier：
    InvivoChem
  • Tel：+1-708-310-1919<br/>+1-13798911105
  • Email：sales@invivochem.cn
  • Country：United States
  • ProdList：6391
  • Advantage：58
OSI-420 Spectrum
183320-51-6, OSI-420Related Search:
  • Inhibitors
  • 抑制剂
  • 生物试剂
  • 药靶配体
  • 蛋白酪氨酸激酶
  • 小分子抑制剂，天然产物
  • C21H21N3O4HCl
  • OSI-420 |CAS 183320-51-6
  • 去甲厄洛替尼,10 MM DMSO 溶液
  • 2-((4-((3-乙炔基苯基)氨基)-7-(2-甲氧基乙氧基)喹唑啉-6-基)氧基)乙醇盐酸盐
  • 2-[[4-[(3-乙炔基苯基)氨基]-7-(2-甲氧基乙氧基)-6-喹唑啉基]氧基]乙醇 盐酸盐 (1:1)
  • 盐酸厄诺替尼
  • 6-O-去甲基厄洛替尼盐酸盐
  • 去甲厄洛替尼盐酸盐
  • O-去甲基埃罗替尼盐酸盐
  • ERLOTINIB O-DESMETHYL METABOLITE ISOMER (M14)盐酸盐
  • 厄洛替尼O-去甲基代谢物异构体
  • 厄洛替尼6-O-脱甲基杂质(盐酸盐)
  • 厄洛替尼O-去甲基代谢物异构体(M14)HCL
  • 厄洛替尼杂质N(盐酸盐)
  • OSI-420去甲厄洛替尼
  • 2-[[4-[(3-乙炔基苯基)氨基]-7-(2-甲氧基乙氧基)-6-喹唑啉基]氧]乙醇盐酸盐
  • 去甲厄洛替尼
  • 去甲基埃罗替尼
  • 盐酸厄洛替尼O-去甲代谢物异构体(M14)
  • 183320-51-6
  • Desmethyl Erlotinib hydrochloride, 10 mM in DMSO
  • 2-[[4-[(3-Ethynylphenyl)amino]-7-(2-methoxyethoxy)-6-quinazolinyl]oxy]ethanol hydrochloride (1:1)
  • OSI-420 CP-473420 O-Desmethylerlotinib hydrochloride salt OSI420
  • OSI-420 (Desmethyl Erlotinib) HCl
  • O-Desmethylerlotinib hydrochloride salt
  • OSI-420 USP/EP/BP
  • Desmethyl Erlotinib hydrochloride
  • O-Desmethylerlotinib hydrochloride
  • Erlotinib O-Desmethyl Metabolite Isomer (M14) Hydrochloride
  • Erlotinib O-Desmethyl Metabolite Isomer HCl
  • 2-((4-((3-ethynylphenyl)amino)-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethan-1-o
  • DESMETHYL ERLOTINIB; CP-473420; OSI420; OSI 420; CP473420; CP 473420
  • 6-O-Desmethyl Erlotinib Hydrochloride
  • 2-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]oxyethanol
  • 7-(2&rsquo
  • Ethanol, 2-[[4-[(3-ethynylphenyl)amino]-7-(2-methoxyethoxy)-6-quinazolinyl]oxy]-, hydrochloride (1:1)
  • OSI420 HCl
  • Desmethyl Erlotinib (OSI-420)
  • 2-[[4-[(3-Ethynylphenyl)amino]-7-(2-methoxyethoxy)-6-quinazolinyl]oxy]ethanol hydrochloride
  • 2-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]oxyethanolhydrochloride
  • DesMethyl Erlotinib (CP-473420) HCl
  • 2-(4-(3-ethynylphenylamino)-7-(2-methoxyethoxy)quinazolin-6-yloxy)ethanol hydrochloride
  • OSI420/OSI-420/Desmethyl erlotinib /O-Desmethylerlotinib hydrochloride
  • 6-O-Desmethyl Erlotinib 2
  • Erlotinib O-DesMethyl Metabolite IsoMer (M14) HCl
  • OSI-420 (DesMethyl Erlotinib)
  • OSI-420 hydrochloride
  • DesMethyl Erlotinib
  • CP-473420
  • OSI-420 (DesMethyl Erlotinib,CP-473420)
  • Ethanol, 2-[[4-[(3-ethynylphenyl)aMino]-7-(2-Methoxyethoxy)-6-quinazolinyl]oxy]-, hydrochloride

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