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Pardoprunox

Pardoprunox Structure
Pardoprunox
  • CAS No.269718-84-5
  • Chemical Name:Pardoprunox
  • CBNumber:CB22498836
  • Molecular Formula:C12H15N3O2
  • Formula Weight:233.27
  • MOL File:269718-84-5.mol
Pardoprunox Property
  • Density 1.258±0.06 g/cm3(Predicted)
  • storage temp. Store at -20°C
  • solubility Soluble in DMSO
  • pka 9.15±0.70(Predicted)
  • FDA UNII 5R72CHP32S
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

Pardoprunox Chemical Properties,Usage,Production

  • Uses Pardoprunox (SLV-308) is a partial dopamine D2 and D3 receptor partial agonist and a serotonin 5-HT1A receptor agonist, with pEC50s of 8, 9.2, and 6.3, respectively[1].
  • IC 50 5-HT1A Receptor: 6.3 (pEC50); D2 Receptor: 8 (pEC50); D3 Receptor: 9.2 (pEC50)
  • References [1] Glennon JC, et al. In vitro characterization of SLV308 (7-[4-methyl-1-piperazinyl]-2(3H)-benzoxazolone, monohydrochloride): a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist. Synapse. 2006 Dec 15;60(8):599-608. DOI:10.1002/syn.20330
    [2] Bronzova J, et al. Double-blind study of pardoprunox, a new partial dopamine agonist, in early Parkinson's disease. Mov Disord. 2010 Apr 30;25(6):738-46. DOI:10.1002/mds.22948
    [3] Bétry C, et al. In vivo effects of pardoprunox (SLV308), a partial D?/D? receptor and 5-HT1A receptor agonist, on rat dopamine and serotonin neuronal activity. Synapse. 2011 Oct;65(10):1042-51. DOI:10.1002/syn.20936
Pardoprunox Preparation Products And Raw materials
Raw materials
Preparation Products
Pardoprunox Suppliers
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Pardoprunox Spectrum
269718-84-5, PardoprunoxRelated Search:
  • Inhibitors
  • 抑制剂
  • 小分子抑制剂，天然产物
  • 小分子抑制剂
  • 帕多芦诺
  • 269718-84-5
  • 2(3H)-Benzoxazolone, 7-(4-methyl-1-piperazinyl)-
  • 7-(4-methylpiperazin-1-yl)-3H-1,3-benzoxazol-2-one
  • Pardoprunox，DU 126891
  • SLV-308; DU-126891
  • SLV-308
  • pardoprunox (SLV308)
  • 7-(4-Methyl-1-piperazinyl)-2(3H)-benzoxazolone
  • DU 126891
  • Pardoprunox

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