ChemicalBook > CAS DataBase List > 1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropylether

1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropylether

1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropylether Structure
1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropylether
  • CAS No.16627-68-2
  • Chemical Name:1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropylether
  • CBNumber:CB2214179
  • Molecular Formula:C5H4F8O
  • Formula Weight:232.07
  • MOL File:16627-68-2.mol
1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropylether Property
  • Boiling point 92 °C
  • Density 1.533
  • refractive index 1.29
  • Flash point 27.5 °C
  • storage temp. Sealed in dry,Room Temperature
  • form clear liquid
  • Specific Gravity 1.533
  • color Colorless to Almost colorless
  • InChI InChI=1S/C5H4F8O/c6-2(7)4(10,11)1-14-5(12,13)3(8)9/h2-3H,1H2
  • InChIKey HCBRSIIGBBDDCD-UHFFFAOYSA-N
  • SMILES C(F)(F)C(F)(F)COC(F)(F)C(F)F
  • CAS DataBase Reference 16627-68-2(CAS DataBase Reference)
  • EPA Substance Registry System (2H-Perfluoroethyl)(1H,1H,3H-perfluoropropyl)ether (16627-68-2)
  • UNSPSC Code 12352100
  • NACRES NA.21
Safety
  • Hazard Codes  :Xi
  • Risk Statements  :36/37/38
  • Safety Statements  :26-36
  • RIDADR  :3271
  • HazardClass  :IRRITANT
  • PackingGroup  :II
  • HS Code  :29091990
  • NFPA 704:
    3
    0 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H226
  • Precautionary statements P501-P240-P210-P233-P243-P241-P242-P280-P370+P378-P303+P361+P353-P403+P235
1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropylether Price More Price(2)
  • Brand: TCI Chemicals (India)
  • Product number: T3069
  • Product name : 1,1,2,2-Tetrafluoroethyl 2,2,3,3-Tetrafluoropropyl Ether
  • Purity: min. 95.0 %
  • Packaging: 5G
  • Price: ₹2700
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: T3069
  • Product name : 1,1,2,2-Tetrafluoroethyl 2,2,3,3-Tetrafluoropropyl Ether
  • Purity: min. 95.0 %
  • Packaging: 25G
  • Price: ₹9600
  • Updated: 2022/05/26
  • Buy: Buy

1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropylether Chemical Properties,Usage,Production

  • Description 1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropyl ether (HFE-458) is a hydrofluoroether. Hydrofluoroether is a new type of  chlorofluorocarbons (CFCs) substitute, ODP is zero, GWP is low, and the atmospheric residence time is very short. It is considered as one of the ideal substitutes for CFCs.
  • Uses 1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropylether can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.
  • Synthesis Synthesis_16627-68-2
    A system of a 6-L autoclave made of stainless steel was evacuated. The autoclave was charged with 401 g of potassium hydroxide (7.15 mol, 0.55 molar amount relative to 1 mol of a fluorine-containing alkyl alcohol), water (1604 mL), 2,2,3,3-tetrafluoro-1-propanol (boiling point of 109?? C., specific gravity of 1.4) represented by HCF2CF2CH2OH (1716 g, 13 mol) as a fluorine-containing alkyl alcohol. Then, the system was evacuated and replaced with nitrogen 20 times at room temperature. After evacuated, the system was filled with tetrafluoroethylene to 0.1 MPa, and the reaction system was heated to 85?? C. After the temperature in the system reached 85?? C., tetrafluoroethylene was added thereto little by little so that the reaction pressure was kept at 0.5 to 0.8 MPa. The temperature in the system was adjusted so as to be kept at 75 to 95?? C.Tetrafluoroethylene was added until the amount reached 0.5 molar relative to 1 mol of the fluorine-containing alkyl alcohol. The reaction was continuously carried out under stirring. When reduction in the pressure in the autoclave was stopped, the temperature in the autoclave was reduced to room temperature and unreacted tetrafluoroethylene was discharged, and the reaction was stopped. These steps took 5 hours to perform.The fluoroether of a lower phase of the production solution was HCF2CF2CH2OCF2CF2H (boiling point of 92?? C., specific gravity of 1.52). Table 1 shows the composition of the fluoroether production solution of a lower phase resulting from GC analysis.
1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropylether Preparation Products And Raw materials
Raw materials
Preparation Products
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1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropylether Spectrum
16627-68-2, 1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropyletherRelated Search:
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  • 有机氟中间体
  • 溶剂
  • 1,1,2,2-四氣乙基-2,2,3,3-四氣丙基醚
  • 1,1,2,2-四氟乙基-2,2,3,3-四氟丙基醚HFE-458
  • 1,1,2,2-四氟乙基-2,2,3,3-四氟丙基醚458
  • 1,1, 2, 2-四氟乙基-2, 2, 3, 3-四氟丙基酷
  • 四氟乙基四氟丙基醚(HFE-458)
  • 四氟乙基四氟丙基醚 HFE458 HFE - 458
  • HFE-458 1,1,2,2-四氟乙基-2,2,3,3-四氟丙基醚
  • 氢氟醚(HFE-458)
  • 氢氟醚-458
  • 1,1,2,2-四氟乙基-2,2,3,3-四氟丙基醚 25G
  • 氢氟醚四氟乙基四氟丙基醚
  • 1,1,2,2-四氟乙基2,2,3,3-四氟丙醚
  • 1,1,2,2-四氟乙基-2,2,3,3-四氟丙基醚
  • 16627-68-2
  • CHLUMOFIUOR CH-458 Tetrafluoroethyl-2,2,3,3-tetrafluoropropyl ether
  • 1,1,1,2,2,3,3-Heptafluoro-3-(1,1,2,2,3,3,3-heptafluoropropoxy)propane
  • 2,2,3,3-Tetrafluoro-1-(1,1,2,2-tetrafluoroethoxy)propan
  • 1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropyl ether HFE-458
  • 1,1,2,2-tetrafluoroethyl-2,3,3-tetrafluoropropane ether HFE-458
  • 1,1,2,2-tetrafluoro-3-(1,1,2,2-tetrafluoroethoxy)propane
  • 1,1,2,2-TETRAFLUOROETHYL 2,2,3,3-TETRAFLUOROPROPYL ETHER
  • HFE458 HFE-458
  • 3-tetrafluoropropylether
  • 2-Tetrafluoroethyl-2
  • 1,1,2,2-Tetrafluoroethyl-2,2,3,3-Tetrafluoropropylether,>98%
  • uoropropyL
  • 2,2,3,3-tetrafL
  • 1,1,2,2-TetrafL
  • HFE-458 /1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropylether
  • HYDROFLUOROETHER-458
  • 2H-Tetrafluoroethyl 2,2,3,3-tetrafluoropropyl ether 98%
  • Propane,1,1,2,2-tetrafluoro-3-(1,1,2,2-tetrafluoroethoxy)-
  • DAIKIN T-5216
  • HYDROFLUOROETHER(HFE-458)
  • 2H-Tetrafluoroethyl 2,2,3,3-tetrafluoropropyl ether
  • 1,1,2,2,5,5,6,6-Octafluoro-3-oxahexane, 1,1,2,2-Tetrafluoro-3-(1,1,2,2-tetrafluoroethoxy)propane
  • product NaMe 2,2,3,3-Tetrafluoro-1-(1,1,2,2-tetrafluoroethoxy)propane
  • 1,1,2,2,5,5,6,6-OCTAFLUORO-3-OXAHEXANE
  • 2,2,3,3-TETRAFLUORO-1-(1,1,2,2-TETRAFLUOROETHOXY)PROPANE