ChemicalBook > CAS DataBase List > 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one

7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one

7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one Structure
7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
  • CAS No.199327-61-2
  • Chemical Name:7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
  • CBNumber:CB21477111
  • Molecular Formula:C16H21N3O4
  • Formula Weight:319.36
  • MOL File:199327-61-2.mol
7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one Property
  • Melting point 233-236 °C
  • Boiling point 519.5±60.0 °C(Predicted)
  • Density 1.32±0.1 g/cm3(Predicted)
  • storage temp. 2-8°C
  • solubility DMSO (Slightly), Methanol (Slightly)
  • form Solid
  • pka 7.10±0.10(Predicted)
  • color White to Off-White
  • CAS DataBase Reference 199327-61-2(CAS DataBase Reference)
  • FDA UNII R9YH59H93M
  • UNSPSC Code 41116107
  • NACRES NA.24
Safety
  • HS Code  :2933599590
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H319-H335-H302+H312+H332-H315
  • Precautionary statements P260-P273-P280-P312

7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one Chemical Properties,Usage,Production

  • Description 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one is a pharmaceutical intermediate used in the preparation of gefitinib, an orally active selective inhibitor of the epidermal growth factor receptor tyrosine kinase, an enzyme that regulates intracellular signalling pathways that associated with the proliferation and survival of cancer cells.
  • Chemical Properties White Solid
  • Uses Gefitinib intermediate.
7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one Preparation Products And Raw materials
Raw materials
Preparation Products
7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one Suppliers
Global(279)Suppliers
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7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one Spectrum
199327-61-2, 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-oneRelated Search:
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Intermediates
  • Heterocycles
  • Gefitinib INTERMEDIATES
  • 医用原料
  • 抑制剂
  • 化学试剂
  • 高端化学
  • 有机原料-杂环化合物
  • 医药原料
  • 杂质对照品
  • 医药杂质对照品
  • 系列1
  • 对照品-杂质对照品
  • 化工中间体
  • 合成材料中间体
  • 吉非替尼杂质
  • 医药中间体
  • 吉非替尼中间体
  • 替尼类
  • 中间体
  • 31936
  • 吉非替尼EP杂质A(吉非替尼USP相关化合物A)
  • 化合物 GEFITINIB IMPURITY 5
  • 吉非替尼杂质135
  • 吉非替尼杂质132
  • 7-甲氧基-6-(3-吗啉-4-丙氧基)-3H-喹唑啉-4-酮 CAS NO. 199327-61-2
  • 7-甲氧基-6-(3-吗啉-4-基丙氧基)喹唑啉-4(3H)-酮(吉非替尼的N-1)
  • 6-[3-(4-吗啉基)丙氧基]-7-甲氧基喹唑啉-4(3H)-酮
  • 7-甲氧基-6-(3-吗啉-4-基丙氧基)喹唑啉-4(3H)-酮,吉非替尼中间体
  • 吉非替尼中间体六
  • 7-甲氧基-6-[3-(吗啉-4-基)-丙氧基]-3,4-二氢喹唑啉-4-酮
  • 7-甲氧基-6-(3-吗啉-4-基丙氧基)-4(3H)-喹唑啉酮
  • 吉非替尼酮
  • 吉非酮
  • 吉非替尼杂质-12
  • 7-甲氧基-6-(3-吗啉-4-基丙氧基)喹唑啉-4
  • 吉非替尼中间体 7-甲氧基-6-(3-吗啉-4-基丙氧基)喹唑啉-4(3H)-酮
  • 7-甲氧基-6-(3-吗啉-4-基丙氧基)喹
  • 7-甲氧基-6-(3-吗啉基-4-丙氧基)喹唑啉-4(3H)-酮
  • 吉非替尼杂质 F
  • 7-甲氧基-6-(3-吗啉-4-基丙氧基)喹唑啉-4(3H)-酮,吉非替尼中间体 1KG
  • 7-甲氧基-6-(3-吗啉-4-基丙氧基)喹唑啉-4(3H)-酮
  • 199327-61-2
  • Gefitinib EP Impurity A (Gefitinib USP Related Compound A)
  • Gefitinib Related Compound A
  • [containing ≥ 0.5 % formamide (EC No 200-842-0) ]
  • [containing < 0.5 % formamide (EC No 200-842-0)]
  • 7-methoxy-6-(4-morpholinobutyl) quinazolin-4(3H)-one
  • 7-Methoxy-6-(3-morpholinopropoxy)quizolin-4(3H)-one
  • 7-methoxy-6- (3-morpholine-4-ylpropyloxy) quinazoline-4 (3H) - one
  • 7-Methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4(1H)-one
  • TIANFU-CHEM - 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
  • Gefitinib impurities132
  • Gefitinib impurities135
  • 7-METHOXY-6-(MORPHOLIN-4-YL PROPY L)QUINAZOLIN-4-(3H)-ONE
  • 4(3H)-Quinazolinone, 7-methoxy-6-[3-(4-morpholinyl)propoxy]-

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