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bruceine E

bruceine E Structure
bruceine E
  • CAS No.21586-90-3
  • Chemical Name:bruceine E
  • CBNumber:CB21340189
  • Molecular Formula:C20H28O9
  • Formula Weight:412.43
  • MOL File:21586-90-3.mol
bruceine E Property
  • form Solid
  • color White to off-white
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

bruceine E Chemical Properties,Usage,Production

  • Uses Bruceine E is a quassinoid from seeds of Brucea javanica (L.) Merr, exhibiting hypoglycemia effect[1]. Bruceine E exhibits blood glucose lowering effect in both nondiabetic mice and Streptozotocin (STZ (HY-13753))-induced diabetic rats at lower dose[2].
  • in vivo

    Bruceine D and E, isolated from B. javanica seeds, exhibits blood glucose lowering effect in both nondiabetic mice and STZ-induced diabetic rats at lower dose (1 mg/kg b.w.) during 0-8 h screening[2].

  • References [1] Man F, et al. HPLC-MS/MS method for bioavailability study of bruceines D & E in rat plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 15;1063:183-188. DOI:10.1016/j.jchromb.2017.08.037
    [2] Ablat A, et al. Antidiabetic effects of Brucea javanica seeds in type 2 diabetic rats. BMC Complement Altern Med. 2017;17(1):94. Published 2017 Feb 6. DOI:10.1186/s12906-017-1610-x
bruceine E Preparation Products And Raw materials
Raw materials
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bruceine E Spectrum
21586-90-3, bruceine ERelated Search:
  • 抑制剂
  • 苦味素
  • 天然产物
  • 二萜
  • 对照品-中药对照品
  • 中药对照品
  • 鸦胆子素E,10 MM DMSO 溶液
  • (1R,2S,3R,3AR,3A1R,4R,6AR,7AS,10S,11S,11AS,11BR)-1,2,3A,4,10,11-六羟基-3,8,11A-三甲基-1,2,3,3A,4,6A,7,7A,10,11,11A,11B-十二氢-5H-3,3A1-(环氧甲桥)二苯并[DE,G]苯并吡喃-5-酮
  • 鸦胆因E
  • 鸦胆苦素E
  • 21586-90-3
  • Bruceine E, 10 mM in DMSO
  • (1R,2S,3R,3aR,3a1R,4R,6aR,7aS,10S,11S,11aS,11bR)-1,2,3a,4,10,11-Hexahydroxy-3,8,11a-trimethyl-1,2,3,3a,4,6a,7,7a,10,11,11a,11b-dodecahydro-5H-3,3a1-(epoxymethano)dibenzo[de,g]chromen-5-one
  • hypoglycemia,quassinoid,Bruceine E,effect,Inhibitor,antidiabetic,inhibit
  • (1R,2S,3R,3aR,3a1R,4R,6aR,7aS,10S,11S,11aS)-1,2,3a,4,10,11-hexahydroxy-3,8,11a-trimethyl-2,3,3a,4,7,7a,10,11,11a,11b-decahydro-1H-3,3a1-(epoxymethano)dibenzo[de,g]chromen-5(6aH)-one
  • Picras-3-en-16-one, 13,20-epoxy-1,2,11,12,14,15-hexahydroxy-, (1β,2α,11β,12α,15β)-
  • Brucein E
  • 2-O-Demethylbruceine M
  • 20-Deoxybruceine F
  • 13,20-Epoxy-1β,2α,11β,12α,14,15β-hexahydroxypicras-3-en-16-one

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