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HYDROXYFASUDIL MONOHYDROCHLORIDE

HYDROXYFASUDIL MONOHYDROCHLORIDE Structure
HYDROXYFASUDIL MONOHYDROCHLORIDE
  • CAS No.155558-32-0
  • Chemical Name:HYDROXYFASUDIL MONOHYDROCHLORIDE
  • CBNumber:CB1973040
  • Molecular Formula:C14H18ClN3O3S
  • Formula Weight:343.82902
  • MOL File:155558-32-0.mol
HYDROXYFASUDIL MONOHYDROCHLORIDE Property
  • Melting point >250 (dec.)
  • storage temp. Inert atmosphere,2-8°C
  • solubility H2O: >5mg/mL
  • form solid
  • color white
  • Water Solubility Soluble in water (20mM)
  • InChIKey XWWFOUVDVJGNNG-UHFFFAOYSA-N
  • UNSPSC Code 12352200
  • NACRES NA.77
Safety
  • Hazard Codes  :Xn
  • Risk Statements  :22
  • WGK Germany  :3
  • NFPA 704:
    0
    2 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302
  • Precautionary statements P264-P270-P301+P312-P501
HYDROXYFASUDIL MONOHYDROCHLORIDE Price More Price(3)
  • Brand: Sigma-Aldrich(India)
  • Product number: H4413
  • Product name : Hydroxyfasudil hydrochloride hydrate
  • Purity: ≥98% (HPLC), solid
  • Packaging: 5MG
  • Price: ₹21476.8
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: H4413
  • Product name : Hydroxyfasudil hydrochloride hydrate
  • Purity: ≥98% (HPLC), solid
  • Packaging: 25MG
  • Price: ₹96667.25
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 390602
  • Product name : Hydroxyfasudil - CAS 155558-32-0 - Calbiochem
  • Purity: A cell-permeable, hydroxylated metabolite of HA 1077 that displays anti-anginal properties.
  • Packaging: 2MG
  • Price: ₹14260
  • Updated: 2022/06/14
  • Buy: Buy

HYDROXYFASUDIL MONOHYDROCHLORIDE Chemical Properties,Usage,Production

  • Chemical Properties Off-White Solid
  • Uses A metabolite of Fasudil. A cell-permeable, hydroxylated metabolite of HA 1077 that displays anti-anginal properties. Reported to inhibit the Rho kinase-mediated (ROCK) contraction both in vitro and in vivo.
  • General Description A cell-permeable, hydroxylated metabolite of HA 1077 (Fasudil; Cat. No. 371970) that displays anti-anginal properties. Acts as an ATP-competitive and a reversible inhibitor of Rho-kinase (IC50 = 0.9 and 1.8 μM using a peptide and MLC as substrate, respectively) with ~100-fold greater selectivity over MLCK, MRCKβ, and PKC. Reported to inhibit the Rho kinase-mediated contraction both in vitro and in vivo.
  • Biochem/physiol Actions Cell permeable: yes
  • storage -20°C
HYDROXYFASUDIL MONOHYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
HYDROXYFASUDIL MONOHYDROCHLORIDE Suppliers
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HYDROXYFASUDIL MONOHYDROCHLORIDE Spectrum
155558-32-0, HYDROXYFASUDIL MONOHYDROCHLORIDERelated Search:
  • Pharmaceuticals
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  • Intermediates & Fine Chemicals
  • Various Metabolites and Impurities
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  • 1-(1-羟基-5-异喹啉磺酰基)高哌嗪盐酸盐
  • RHO-激酶抑制剂
  • 羟基法舒地尔
  • 羟基法舒地尔盐酸盐
  • 155558-32-0
  • Hydroxyfasudil Hydrochloride, 10 mM in DMSO
  • HA 1100 hydrochloride (Hydroxyfasudil), Rho-kinase inhibitor
  • HA 1100 hydrochloride (Hydroxyfasudil)
  • Hydroxyfasudil hydrochloride hydrate Hydroxyfasudil hydrochloride
  • HA-1100,ROCK,Hydroxyfasudil Hydrochloride,Hydroxyfasudil,Rho-associated kinase,HA 1100,inhibit,HA1100,Rho-kinase,Rho-associated protein kinase,ROK,Inhibitor
  • 5-(1,4-diazepan-1-ylsulfonyl)-2H-isoquinolin-1-one,hydrochloride
  • Hydroxyfasudil HCl (HA1100)
  • 5-[(1,4-Diazepan-1-yl)sulfonyl]isoquinolin-1(2H)-one Hydrochloride
  • 5-((1,4-diazepan-1-yl)sulfonyl)isoquinolin-1-ol hydrochloride
  • Fasudil Hydroxy
  • Fasudil Impurity 7 HCl
  • 1(2H)-Isoquinolinone, 5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-, hydrochloride (1:1)
  • Hydroxyfasudil (HA-1100) HCl
  • Hydroxyfasudil HCl
  • Hydroxyfasudil - CAS 155558-32-0 - Calbiochem
  • Hydroxyfasudil hydrochloride (HA-1100 hydrochloride)
  • 5-(1,4-diazepan-1-ylsulfonyl)-2h-isoquinolin-1-one
  • HA-1100 HYDROCHLORIDE;HA 1100 HYDROCHLORIDE;HA1100 HYDROCHLORIDE
  • Hydroxyfasudil (HA-1100)
  • Hydroxyfasudil hydrochloride hydrate
  • 1-(1-Hydroxy-5-isoquinolinesulfonyl)homopiperazine hydrochloride hydrate
  • Hydroxyfasudil hydrochloride hydrate,1-(1-Hydroxy-5-isoquinolinesulfonyl)homopiperazine hydrochloride hydrate
  • HYDROXYFASUDIL MONOHYDROCHLORIDE
  • 1-(1-hydroxy-5-isoquinolinesulfonyl)homopiperazine monohydrochloride
  • Hydroxyfasudil Hydrochloride
  • 5-[(Hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-1(2H)-isoquinolinone

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