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9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate

9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate Structure
9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate
  • CAS No.206184-49-8
  • Chemical Name:9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate
  • CBNumber:CB1855342
  • Molecular Formula:C9H16N5O5P
  • Formula Weight:305.23
  • MOL File:206184-49-8.mol
9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate Property
  • Melting point 270-274oC
  • storage temp. 2-8°C
  • solubility Aqueous Acid (Slightly), DMSO (Slightly)
  • form Solid
  • color White to Off-White
  • Stability Hygroscopic
  • FDA UNII 99YXE507IL
  • UNSPSC Code 41116107
  • NACRES NA.24
Safety
  • HS Code  :2933599550
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H301
  • Precautionary statements P301+P330+P331+P310
9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate Price More Price(1)
  • Brand: Sigma-Aldrich(India)
  • Product number: PHR1592
  • Product name : Tenofovir
  • Purity: Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging: 1G
  • Price: ₹16280.8
  • Updated: 2022/06/14
  • Buy: Buy

9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate Chemical Properties,Usage,Production

  • Chemical Properties WHITE POWDER SOLID
  • Uses antineoplastic, thymidylate synthase inhibitor
  • Uses Tenofovir Monohydrate is an HIV-1 RT inhibitor and antiretroviral drug.
  • Definition ChEBI: A hydrate that is the monohydrate form of anhydrous tenovir.
  • General Description Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Tenofovir is a nucleotide analog reverse transcriptase inhibitor, and is widely used as an antiretroviral agent, for the treatment of HIV infection.
  • Biological Activity tenofovir hydrate is an inhibitor of reverse transcriptase used for the treatment of the human immunodeficiency virus 1(hiv-1) and hepatitis b [1].tenofovir hydrate is an antiviral pro-drug and the class of nucleoside reverse transcriptase inhibitor. in addition, tenofovir hydrate has been reported to have a dependent relation between intracellular the drug concentrations and prevent function of hiv-1infection with ec50 values of 29 fmol/106, 40 fmol/106 , 77 fmol/106 and 411 fmol/106 cells for inoculum size 1, 5, 20 and 100 respectively. and the ec90 values of tenofovir hydrate are 267 fmol/106, 348 fmol/106, 640 fmol/106 and 2866 fmol/106 cells for virus inoculums size 1, 5, 20 and 100, respectively [1].
  • References [1] duwal s1, schütte c, von kleist m.pharmacokinetics and pharmacodynamics of the reverse transcriptase inhibitor tenofovir and prophylactic efficacy against hiv-1 infection. plos one. 2012;7(7):e40382. doi: 10.1371/journal.pone.0040382. epub 2012 jul 11.
9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate Preparation Products And Raw materials
Raw materials
Preparation Products
9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate Suppliers
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9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate Spectrum
206184-49-8, 9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrateRelated Search:
  • ALIMTA
  • 化学试剂
  • 抑制剂
  • 药靶配体
  • 医药原料药API
  • 杂质对照品
  • 对照品
  • 医药原料
  • 泰诺福韦系列
  • 对照品-杂质对照品
  • 泰诺福韦中间体
  • 医药中间体
  • C9H16N5O5P
  • C9H14N5O4PH2O
  • 泰诺福韦一水合物
  • 替诺福韦 CRS
  • 化合物 T1649L
  • 泰诺福韦单水合物(PMPA)
  • (R)-((1-(6-氨基-9H-嘌呤-9-基)丙烷-2-基)氧基)甲基)膦酸水合物
  • 替诺福韦(含水)
  • 泰诺福韦 USP标准品
  • 替诺福韦一水物
  • 替诺福韦一水化合物
  • (R)-(((1-(6-氨基-9H-嘌呤-9-基)丙烷-2-基)氧基)甲基)磷酸 水合物
  • 9-[(R)-2-(磷酰甲氧基)丙基]腺嘌呤(含水)
  • 替诺福韦单水合物
  • 9-[(R)-2-(磷酰甲氧基)丙基]腺嘌呤(一水物)
  • 替诺福韦一水合物
  • 9-(R)-2-(磷酰甲氧基)丙基腺嘌呤(R-PMPA)
  • 9-[(R)-2-(磷酰甲氧基)丙基]腺嘌呤
  • 206184-49-8
  • 9-[(R)-2-(Phosphorylmethoxy)propyl]adenine
  • 9-[(R)-2-(Phosphonomethoxy)propyl] adenine monohydrate [PMPA]
  • Tenofovir hydrate (1:1)
  • Tenofovir CRS
  • ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid hydrate
  • Tenofovir hydrate (GS 1278)
  • P-[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic Acid Hydrate
  • Tenofovir (1643601)
  • 9-[(R)-2-(Phosphonomethoxy)propyl]adenine 1-hydrate
  • Phosphonic acid, P-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, hydrate (1:1)
  • Tenofovir(H2O)
  • R-PMPA of Tenofovir
  • [(1R)-2-(6-aminopurin-9-yl)-1-methyl-ethoxy]methylphosphonic acid
  • (R)-9-(2-phosphonylmethoxy propyl)adenine(R-PMPA)
  • (r)-[[2-(6-amino-9h-purin-9-yl)-1-methylethoxy]methyl]-phosphonic acid monohydrate
  • (R)-(((1-(6-Amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonic acid hydrate
  • PMPA Monohydrate
  • [[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic acid monohydrate
  • Tenofovir (hydrate)
  • Tenofovir (15 mg)
  • Tenofovir Monohydrate
  • Unii-99yxe507il
  • 9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate

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