Nolatrexed
- Product NameNolatrexed
- CAS147149-76-6
- CBNumberCB1765629
- MFC14H12N4OS
- MW284.34
- EINECS1533716-785-6
- MDL NumberMFCD26960887
- MOL File147149-76-6.mol
Chemical Properties
| Melting point: | 301-302° |
Nolatrexed Chemical Properties,Usage,Production
Uses
Nolatrexed (AG 337 free base) is a compound with antifolate activity, high oral bioavailability, and major toxicity at inhibitory doses is gastrointestinal reactions. It can be safely taken orally at specific doses for inhibition, with effects on platelets and neutrophils.References
[1] Phase I studies with the nonclassical antifolate nolatrexed dihydrochloride (AG337, THYMITAQ) administered orally for 5 days PMID:9918208Nolatrexed Supplier
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Nolatrexed Spectrum
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