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PAI-1

PAI-1 Structure
PAI-1
  • CAS No.
  • Chemical Name:PAI-1
  • CBNumber:CB1438644
  • Molecular Formula:C27H47N9O9S
  • Formula Weight:673.78
  • MOL File:Mol file
PAI-1 Property
  • storage temp. -70°C
  • form liquid
  • UNSPSC Code 12352200
  • NACRES NA.77
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

PAI-1 Chemical Properties,Usage,Production

  • Biological Activity Cell permeable: no', 'Primary Target
    Tissue plasminogen activator (tPA) and urokinase (uPA)', 'Product does not compete with ATP.', 'Reversible: no
  • Enzyme inhibitor This 402-residue serine protease inhibitor, or serpin (MW = 45074 g/mol; Abbreviation: PAI-1) binds to and inhibits plasminogen activators-tissuetype plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA). This inhibition reduces plasmin production and suppresses dissolution of fibrin clots. Elevated PAI-1 levels correlate with an increased cardiovascular disease risk, a behavior that has also been linked to obesity and metabolic syndrome. Pharmacological suppression of PAI-1 is a likely way to prevent or treat vascular disease. Reduced PAI-1 levels may result in increased fibrinolysis and an associated bleeding diathesis. PAI-1 was initially identified in the 1980s, and the first reported case of PAI-1 deficiency appeared in 1989. Unambiguous proof that PAI-1 deficiency as a cause of a bleeding disorder has been rare, but use of selective PAI inhibitors (See PAI-749) may clarify this point. Because of lack of standardized commercially available PAI-1 activity assay sensitive in the lowest range, the true prevalence of this rare condition has yet to be established.
PAI-1 Preparation Products And Raw materials
Raw materials
Preparation Products
PAI-1 Suppliers
Global(41)Suppliers
  • Supplier： Bio Rad Laboratories Inc
  • Tel：65-64153170
  • Email：Sales.China@bio-rad.com
  • Country：China
  • ProdList：10054
  • Advantage：58
  • Supplier： Enzo Biochem Inc
  • Tel：Enzo Biochem Inc.<br/>13797054060
  • Email：Enzoname@qq.com
  • Country：China
  • ProdList：177174
  • Advantage：58
  • Supplier： Merck KGaA
  • Tel：21-20338288
  • Email：ordercn@merckgroup.com
  • Country：China
  • ProdList：292394
  • Advantage：58
  • Supplier： Signalway Antibody LLC
  • Tel：025-58868422
  • Email：info@sabbiotech.com
  • Country：China
  • ProdList：99242
  • Advantage：58
  • Supplier： United States Biological
  • Tel：--
  • Email：sales@advtechind.com
  • Country：United States
  • ProdList：6075
  • Advantage：58
PAI-1 Spectrum
  • enzyme
  • 抗体-一抗
  • 试剂盒-Elisa试剂盒
  • BF647标记的内皮细胞纤溶酶原激活抑制蛋白1抗体
  • BF488标记的内皮细胞纤溶酶原激活抑制蛋白1抗体
  • BF594标记的内皮细胞纤溶酶原激活抑制蛋白1抗体
  • RBITC标记的内皮细胞纤溶酶原激活抑制蛋白1抗体
  • BF488标记的纤溶酶原激活物抑制因子抗体
  • CY7标记的内皮细胞纤溶酶原激活抑制蛋白1抗体
  • APC标记的内皮细胞纤溶酶原激活抑制蛋白1抗体
  • 纤溶酶原激活物抑制因子重组兔单抗
  • BF350标记的纤溶酶原激活物抑制因子抗体
  • CY5标记的内皮细胞纤溶酶原激活抑制蛋白1抗体
  • CY3标记的内皮细胞纤溶酶原激活抑制蛋白1抗体
  • PERCP标记的纤溶酶原激活物抑制因子抗体
  • CY3标记的纤溶酶原激活物抑制因子抗体
  • RBITC标记的纤溶酶原激活物抑制因子抗体
  • PE标记的内皮细胞纤溶酶原激活抑制蛋白1抗体
  • APC标记的纤溶酶原激活物抑制因子抗体
  • PERCP-CY7标记的纤溶酶原激活物抑制因子抗体
  • AP标记的纤溶酶原激活物抑制因子抗体
  • CY5.5标记的内皮细胞纤溶酶原激活抑制蛋白1抗体
  • BIOTIN标记的纤溶酶原激活物抑制因子抗体
  • BF680标记的纤溶酶原激活物抑制因子抗体
  • BF405标记的纤溶酶原激活物抑制因子抗体
  • PE-CY7标记的纤溶酶原激活物抑制因子抗体
  • BF555标记的内皮细胞纤溶酶原激活抑制蛋白1抗体
  • PERCP-CY5.5标记的纤溶酶原激活物抑制因子抗体
  • BIOTIN标记的内皮细胞纤溶酶原激活抑制蛋白1抗体
  • CY5标记的纤溶酶原激活物抑制因子抗体
  • BF750标记的内皮细胞纤溶酶原激活抑制蛋白1抗体
  • BF594标记的纤溶酶原激活物抑制因子抗体
  • PE-CY5标记的纤溶酶原激活物抑制因子抗体
  • BF750标记的纤溶酶原激活物抑制因子抗体
  • BF555标记的纤溶酶原激活物抑制因子抗体
  • HRP标记的纤溶酶原激活物抑制因子抗体
  • CY5.5标记的纤溶酶原激活物抑制因子抗体
  • BF680标记的内皮细胞纤溶酶原激活抑制蛋白1抗体
  • APC-CY7标记的纤溶酶原激活物抑制因子抗体
  • CY7标记的纤溶酶原激活物抑制因子抗体
  • PE标记的纤溶酶原激活物抑制因子抗体
  • PE-CY5.5标记的纤溶酶原激活物抑制因子抗体
  • BF647标记的纤溶酶原激活物抑制因子抗体
  • APC-CY5.5标记的纤溶酶原激活物抑制因子抗体
  • AP标记的内皮细胞纤溶酶原激活抑制蛋白1抗体
  • BF405标记的内皮细胞纤溶酶原激活抑制蛋白1抗体
  • HRP标记的内皮细胞纤溶酶原激活抑制蛋白1抗体
  • 纤溶酶原激活物抑制因子1
  • ANTI-PAI1 ANTIBODY-内皮细胞纤溶酶原激活抑制蛋白1抗体
  • ANTI-PAI1 ANTIBODY -纤溶酶原激活物抑制因子抗体
  • Plasminogen Activator Inhibitor Type 1, active, Porcine Assay Kit, BioAssay&trade
  • Plasminogen Activator Inhibitor Type 1, active, Rabbit Assay Kit, BioAssay&trade
  • Plasminogen Activator Inhibitor Type 1, active, Human, Assay Kit, BioAssay&trade
  • Plasminogen Activator Inhibitor Type 1, Mouse Assay Kit, BioAssay&trade
  • Plasminogen Activator Inhibitor Type 1, active, Rat Assay Kit, BioAssay&trade
  • Plasminogen Activator Inhibitor Type 1, active, Mouse Assay Kit, BioAssay&trade
  • PLASMINOGEN ACTIVATOR INHIBITOR-1, RAT, RECOMBINANT
  • PLASMINOGEN ACTIVATOR INHIBITOR-1, RAT

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