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tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate

tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Structure
tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate
  • CAS No.1201187-44-1
  • Chemical Name:tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate
  • CBNumber:CB13102742
  • Molecular Formula:C18H20N4O4S
  • Formula Weight:388.44
  • MOL File:1201187-44-1.mol
tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Property
  • Density 1.35±0.1 g/cm3(Predicted)
  • pka 9.45±0.43(Predicted)
  • InChI InChI=1S/C18H20N4O4S/c1-12-5-7-13(8-6-12)27(24,25)22-10-9-14-16(22)19-11-15(20-14)21-17(23)26-18(2,3)4/h5-11H,1-4H3,(H,20,21,23)
  • InChIKey NTMJGYRFMXFNIC-UHFFFAOYSA-N
  • SMILES C(OC(C)(C)C)(=O)NC1=CN=C2N(S(C3=CC=C(C)C=C3)(=O)=O)C=CC2=N1
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H317
  • Precautionary statements P280

tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Chemical Properties,Usage,Production

  • Uses tert-Butyl N-[5-(4-methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate is a reagent in the synthetic preparation of tricyclic heterocycles and their kinase inhibitory activity. Preparation of novel nitrogen-containing tricyclic compounds as kinase inhibitors for treating immunological and oncological conditions.
  • Uses Tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate, also known as upadacitinib intermediate 2, could be used in the synthesis and property studies of upadacitinib. This compound Often used as organic synthesis intermediates and pharmaceutical intermediates. It can be used in laboratory research processes and chemical production processes.
tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Preparation Products And Raw materials
Raw materials
Preparation Products
tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Suppliers
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tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Spectrum
1201187-44-1, tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamateRelated Search:
  • 系列1
  • 杂质对照品
  • 化工原料及中间体
  • 乌帕替尼中间体
  • 乌帕替尼系列
  • 化工中间体-化工原料
  • 化学试剂-精细化工
  • 化学试剂
  • 叔丁基(5-甲苯磺酰基-5H-吡咯并[2,3-B]吡嗪-2-基)氨基甲酸酯
  • (5-对甲基苯磺酰基-5H-吡咯并[2,3-B]吡嗪-2-基)氨基甲酸叔丁酯
  • N-[5-[(4-METHYLPHENYL)SULFONYL]-5H-PYRROLO[2,3-B]PYRAZIN-2-YL]CARBAMIC ACID1,1-DIMETHYLETHYL ESTERN-[5-[(4-甲基苯基)磺酰基]-5H-吡咯并[2,3-B]吡嗪-2-基]氨基甲酸叔丁酯
  • N-[5-[(4-甲基苯基)磺酰基]-5H-吡咯并[2,3-B]吡嗪-2-基]氨基甲酸叔丁酯/N-[5-[(4-METHYLPHENYL)SULFONYL]-5H-PYRROLO[2,3-B]PYRAZIN-2-YL]CARBAMIC ACID 1,1-DIMETHYLETHYL ESTER
  • 乌帕替尼 中间体4
  • 乌帕替尼杂质3
  • TERT-BUTYL 5-TOSYL-5H-PYRROLO[2,3-B]PYRAZIN-2-YLCARBAMATE 5-甲苯磺酰基-5H-吡咯并[2,3-B]吡嗪-2-胺基甲酸叔丁酯
  • N- [5-[(4-甲基苯基)磺酰基] -5H-吡咯并[2,3-B]吡嗪-2-基]-氨基甲酸,1,1-二甲基乙酯
  • 乌帕替尼中间体2
  • 乌帕替尼/UPADACITINIB中间体
  • N- [5 - [(4-甲基苯基)磺酰基] -5H-吡咯并[2,3-B]吡嗪-2-基] - 氨基甲酸1,1-二甲基乙基酯
  • N-[5-(4-甲基苯磺酰基)-5H-吡咯并[2,3-B]吡嗪-2-基]氨基甲酸叔丁酯
  • (5-对甲基苯磺酰基-5H-吡唑并[2,3-B]吡嗪-2-基)氨基羧酸叔丁酯
  • 5-甲苯磺酰-5H-吡咯并[2,3-B]吡嗪-2-基氨基甲酸叔丁酯
  • 5-甲苯磺酰基-5H-吡咯并[2,3-B]吡嗪-2-胺基甲酸叔丁酯
  • ABT-494中间体-2
  • 1201187-44-1
  • tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbama
  • 1,1-Dimethylethyl N-[5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate
  • Upadacitinib Intermediates
  • N-[5-[(4-Methylphenyl)sulfony!]-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamic, acid 1, 1-dimethylethyl ester
  • tert-butyl N-[5-(4-methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate
  • Upadacitinib Intermediate4
  • Upadacitinib Impurity 3
  • N-[5-[(4-Methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-y...
  • 2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine
  • Upadacitinib intermediate2
  • 2-Methyl-2-propanyl {5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl}carbamate
  • Intermediate of Upadacitinib (ABT-494)
  • tert-butyl (5-(p-toluenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl)carbamate
  • Carbamic acid, N-?[5-?[(4-?methylphenyl)?sulfonyl]?-?5H-?pyrrolo[2,?3-?b]?pyrazin-?2-?yl]?-?, 1,?1-?dimethylethyl ester
  • tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate

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