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N-Boc-PEG5-alcohol

N-Boc-PEG5-alcohol Structure
N-Boc-PEG5-alcohol
  • CAS No.1404111-67-6
  • Chemical Name:N-Boc-PEG5-alcohol
  • CBNumber:CB13053725
  • Molecular Formula:C15H31NO7
  • Formula Weight:337.41
  • MOL File:1404111-67-6.mol
N-Boc-PEG5-alcohol Property
  • Boiling point 451.5±40.0 °C(Predicted)
  • Density 1.083±0.06 g/cm3(Predicted)
  • solubility Soluble in DCM, Methanol
  • pka 12.23±0.46(Predicted)
  • form liquid
  • color Colourless to light yellow
Safety
  • HS Code  :2924190090
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H335
  • Precautionary statements P280-P305+P351+P338

N-Boc-PEG5-alcohol Chemical Properties,Usage,Production

  • Description N-Boc-PEG5-alcohol is a PEG linker containing a hydroxyl group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The Boc group can be deprotected under mild acidic conditions to form the free amine.
  • Uses N-Boc-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
  • IC 50 PEGs; Alkyl/ether
  • References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N-Boc-PEG5-alcohol Preparation Products And Raw materials
Raw materials
Preparation Products
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N-Boc-PEG5-alcohol Spectrum
1404111-67-6, N-Boc-PEG5-alcoholRelated Search:
  • peg
  • 抑制剂
  • PEG系列产品-Boc-PEG系列
  • 药靶配体
  • 助剂
  • 合成材料中间体
  • 其它
  • 基准试剂
  • 化合物 N-BOC-PEG5-ALCOHOL
  • 叔丁氧羰基-PEG5-羟基
  • 氨基叔丁酯-五聚乙二醇
  • (14-羟基-3,6,9,12-四氧杂十四烷基)氨基甲酸叔丁酯
  • N-BOC-PEG5-ALCOHOL,BOCNH-PEG5-OH
  • 叔丁氧羰基五聚乙二醇
  • 叔丁氧羰基五聚乙二醇羟基
  • 氨基叔丁酯-五聚乙二醇-羟基
  • 叔丁氧酰胺-五聚乙二醇
  • 五聚乙二醇-叔丁氧羰基 1G
  • 五聚乙二醇-叔丁氧羰基
  • 1404111-67-6
  • t-Boc-Amido-PEG5-Alcohol
  • BocNH-PEG5-alcohol
  • Boc- NH-PEG5
  • BocNH-PEG5-OH/5,8,11,14-Tetraoxa-2-azahexadecanoic acid, 16-hydroxy-, 1,1-dimethylethyl ester
  • tert-Butyl (14-hydroxy-3,6,9,12-tetraoxatetradecyl)carbamate
  • BocNH-P5-alcohol
  • t-boc-N-amido-PEG5-alcohol
  • 5,8,11,14-Tetraoxa-2-azahexadecanoic acid, 16-hydroxy-, 1,1-dimethylethyl ester
  • NHBoc-PEG5-OH
  • tert-Butyl N-2-2-2-2-(2-hydroxyethoxy)ethoxyethoxyethoxyethylcarbamate
  • Boc-NH-PEG5-OH
  • N-Boc-PEG5-alcoh
  • N-Boc-PEG5-alcohol