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(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID

(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID Structure
(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID
  • CAS No.16626-02-1
  • Chemical Name:(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID
  • CBNumber:CB1274150
  • Molecular Formula:C11H11FN2O2
  • Formula Weight:222.22
  • MOL File:16626-02-1.mol
(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID Property
  • Melting point 238-239 °C
  • Boiling point 450.7±45.0 °C(Predicted)
  • Density 1.442±0.06 g/cm3(Predicted)
  • storage temp. 2-8°C
  • form powder
  • pka 2.21±0.10(Predicted)
  • color white
  • BRN 5052680
  • FDA UNII 17H03VO4KZ
  • UNSPSC Code 12352209
  • NACRES NA.77
Safety
  • Safety Statements  :22-24/25
  • WGK Germany  :3
  • F  :10
  • HS Code  :2933998090
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P261-P305+P351+P338
(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID Price More Price(1)
  • Brand: Sigma-Aldrich(India)
  • Product number: 47568
  • Product name : 5-Fluoro-L-tryptophan
  • Purity: ≥98.0% (HPLC)
  • Packaging: 25MG
  • Price: ₹8080
  • Updated: 2022/06/14
  • Buy: Buy

(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID Chemical Properties,Usage,Production

  • Uses Exogenous 5-fluoro-Trp is incorporated into proteins in normal protein synthesis. Since 19F is a useful reporter group, this provides a method for studying enzyme mechanisms by NMR.
  • Biochem/physiol Actions 5-Fluoro-Trp is nonspecifically cytotoxic. It is believed this is due to malfunctioning enzymes that have had replacements of Trp residues by 5-fluoro-Trp. However, at least one case is known where 5-fluoro-Trp substitution leads to significantly greater catalytic activity.
  • Purification Methods Recrystallise it from EtOH, aqueous EtOH or AcOH. Also purify it by passage through a Dowex AG1x2 (acetate form) column and recrystallise the L-enantiomer (from enzymic enrichment) from H2O/EtOH, m 158-163o(dec), [] D -8.3o (c 2.5, N NaOH). [Coy et al. Biochemistry 13 3550 1974, Beilstein 22/14 V 116.]
(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID Preparation Products And Raw materials
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(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID Spectrum
16626-02-1, (S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACIDRelated Search:
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  • C11H11FN2O2H2O
  • 色氨酸杂质47
  • 5-FLUORO-<SC>L</SC>-TRYPTOPHAN
  • 色氨酸杂质54
  • (S)-2-氨基-3-(5-氟-1H-吲哚-3-基)-丙酸
  • L-5-氟色氨酸
  • 5-氟-L-色氨酸
  • 16626-02-1
  • L-Trp(5-F)-OH
  • 5-fluoro-L-tryptophans
  • Tryptophan Impurity 54
  • 5-Fluoro-L-tryptophan >=98.0% (HPLC)
  • (2S)-2-amino-3-(5-fluoro-1H-indol-3-yl)propanoic acid
  • L-Tryptophan, 5-fluoro-
  • (S)-2-AMino-3-(5-fluoro-1H-indol-3-yl)propanoic acid
  • (S)-α-Amino-5-fluoro-1H-indole-3-propionic acid
  • (S)-5-Fluoro-α-amino-1H-indole-3-propionic acid
  • L-5-fluorotryptophan monohydrate
  • H-L-Trp(5-F)-OH*H2O
  • 5-Fluoro-tryptophan monohydrate
  • (S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID
  • L-5-FLUOROTRYPTOPHAN
  • H-5-FLUORO-TRP-OH H2O
  • 5-FLUORO-L-TRYPTOPHAN MONOHYDRATE
  • 5-FLUORO-L-TRYPTOPHAN

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