ChemicalBook > CAS DataBase List > 2-Bromo-5-ethynylpyridine
2-Bromo-5-ethynylpyridine
2-Bromo-5-ethynylpyridine
- CAS No.569672-28-2
- Chemical Name:2-Bromo-5-ethynylpyridine
- CBNumber:CB12665079
- Molecular Formula:C7H4BrN
- Formula Weight:182.02
- MOL File:569672-28-2.mol
2-Bromo-5-ethynylpyridine Property
- Melting point 83℃
- Boiling point 231.0±25.0 °C(Predicted)
- Density 1.60±0.1 g/cm3(Predicted)
- storage temp. 2-8°C
- pka -0.73±0.10(Predicted)
- InChI InChI=1S/C7H4BrN/c1-2-6-3-4-7(8)9-5-6/h1,3-5H
- InChIKey WRORYOXBXUUDJL-UHFFFAOYSA-N
- SMILES C1(Br)=NC=C(C#C)C=C1
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H302-H315-H320-H335
- Precautionary statements P261-P280-P301+P312-P302+P352-P305+P351+P338
2-Bromo-5-ethynylpyridine Chemical Properties,Usage,Production
- Uses 2-Bromo-5-ethynylpyridine is used in the synthesis of macrocycle of terpyridine units.
-
Preparation
The iodobromopyridine (2-Bromo-5-iodopyridine), the starting material, was coupled with TMS-acetylene under Sonogashira conditions. One-pot deprotection and recrystallization could yield the bromo,ethynyl-functionalized pyridine (2-Bromo-5-ethynylpyridine)[1].
- Reactions 2-Bromo-5-ethynylpyridine is a useful organic compound that could be used to synthesize 2-Bromo-5-[(3-iodophenyl)ethynyl]pyridine, 2-bromo-5-({4-[(tert-butyldimethylsilyl)oxy]phenyl}ethynyl)pyridine, and so on.
2-Bromo-5-ethynylpyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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- 2-溴-5-炔基吡啶
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- 569672-28-2
- Pyridine, 2-bromo-5-ethynyl-
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