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CYCLO (ARG-GLY-ASP-D-PHE-LYS)

CYCLO (ARG-GLY-ASP-D-PHE-LYS) Structure
CYCLO (ARG-GLY-ASP-D-PHE-LYS)
  • CAS No.161552-03-0
  • Chemical Name:CYCLO (ARG-GLY-ASP-D-PHE-LYS)
  • CBNumber:CB1186608
  • Molecular Formula:C27H41N9O7
  • Formula Weight:603.67
  • MOL File:Mol file
CYCLO (ARG-GLY-ASP-D-PHE-LYS) Property
  • Melting point 191℃ (decomposition)
  • Density 1.47±0.1 g/cm3(Predicted)
  • storage temp. Store at -20°C
  • solubility ≥30.19 mg/mL in DMSO; insoluble in EtOH; ≥59.2 mg/mL in H2O
  • form Powder
  • pka 4.01±0.10(Predicted)
  • color White to off-white
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H335
  • Precautionary statements P261-P305+P351+P338

CYCLO (ARG-GLY-ASP-D-PHE-LYS) Chemical Properties,Usage,Production

  • Uses Cyclo (-RGDfK) Trifluoroacetic Acid Salt is a potent inhibitor of αvβ3 integrin. Used in tumor therapy due to the targeting of the VEGFR2 gene by sRNA.
  • Biological Activity in one study where this peptide was labeled with 125i, it was found to bind specifically and with high affinity to αvβ3 receptors on neovascular blood vessel sections of different major human cancers. the integrin alpha(iib)beta(3)-specific cyclic hexapeptide contains an arg-gly-asp (rgd) sequence.
  • target Integrin
  • IC 50 αvβ3: 0.94 nM (IC50)
CYCLO (ARG-GLY-ASP-D-PHE-LYS) Preparation Products And Raw materials
Raw materials
Preparation Products
CYCLO (ARG-GLY-ASP-D-PHE-LYS) Suppliers
Global(148)Suppliers
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CYCLO (ARG-GLY-ASP-D-PHE-LYS) Spectrum
  • RGD
  • peptide
  • 目录多肽
  • 信号转导通路激酶抑制剂
  • 多肽合成
  • 环肽
  • 药靶配体
  • 优势产品
  • 标准品
  • 目录肽
  • 多肽-客户肽
  • 抑制剂
  • 细胞生物学试剂
  • 多肽
  • C27H41N9O7
  • 环状多肽
  • 化合物CYCLO (-RGDFK),10 MM DMSO 溶液
  • 2-((2S,5R,8S,11S)-8-(4-氨基丁基)-5-苄基-11-(3-胍丙基)-3,6,9,12,15-五氧代-1,4,7,10,13-五氮杂环十五烷-2-基)乙酸
  • 整合素抑制剂多肽
  • 环(L-精氨酰甘氨酰-L-Α-天冬氨酰-D-苯丙氨酰-L-赖氨酰)
  • 五元环肽
  • 环(-RGDFK)
  • ΑVΒ3 INTEGRIN抑制剂
  • RGD(D-F)K,RGD环肽,(ARG-GLY-ASP-DPHE-LYS) 环肽
  • 161552-03-0
  • Cyclo (-RGDfK) - 1 mg
  • Cyclo(-RGDfK), 10 mM in DMSO
  • 2-((2S,5R,8S,11S)-8-(4-Aminobutyl)-5-benzyl-11-(3-guanidinopropyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl)acetic acid
  • RGDFK
  • ARG-GLY-ASP-D-PHE-LYS
  • Cyclo(-RGDfK),inhibit,Microvasculature,cancer,Integrin,tumoral cell,αvβ3 integrin,Cyclo(RGDfK),ligand,Inhibitor,Cyclo( RGDfK)
  • cyclo(RGD-DPhe-K)
  • CYCLO
  • Cyclo(RGDfK) peptide
  • c(RGDfK)
  • CYCLO(-RGDFK)
  • CYCLO (ARG-GLY-ASP-D-PHE-LYS) USP/EP/BP
  • Cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-L-lysyl)
  • Cyclo(-RGDfK), >98%
  • C(RGDFK);CYCLO (RGDFK)
  • Cyclo(-RGDfK)(free base)
  • CYCLO(RGDFK) PEPTIDE;CYCLIC RGDFK PEPTIDE
  • Cyclo (-RGDfK) TFA
  • Cyclo(-Arg-Gly-Asp-D-Phe-Lys) Trifluoroacetate salt
  • Cyclo(L-arginylglycyl-L-alpha-aspartyl-D-phenylalanyl-L-lysyl)
  • Cyclic RGDFK peptide
  • cyclo (Arg-Gly-Asp-Phe-Lys)
  • CYCLO (ARG-GLY-ASP-D-PHE-LYS)

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