ChemicalBook > CAS DataBase List > α-Muricholic Acid
α-Muricholic Acid
- CAS No.2393-58-0
- Chemical Name:α-Muricholic Acid
- CBNumber:CB11235695
- Molecular Formula:C24H40O5
- Formula Weight:408.58
- MOL File:2393-58-0.mol
α-Muricholic Acid Property
- Melting point 200-202 °C
- Boiling point 565.7±40.0 °C(Predicted)
- Density 1.184±0.06 g/cm3(Predicted)
- storage temp. Refrigerator
- solubility DMSO (Slightly), Methanol (Slightly)
- form Solid
- pka 4.76±0.10(Predicted)
- color White to Off-White
- UNSPSC Code 12352211
- NACRES NA.25
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
α-Muricholic Acid Chemical Properties,Usage,Production
- Description α-Muricholic acid is a murine-specific primary bile acid. Dietary administration of soybean protein decreases fecal levels of α-muricholic acid in mice with high-fat diet-induced obesity which correlates with increases in fecal Clostridium cluster XIVa, a major producer of secondary bile acids. Plasma, liver, and muscle levels of α-muricholic acid are increased in mice switched from a high-fat to low-fat diet.
- Uses α-Muricholic Acid is an bile acid found in urine. Studies have linked α-Muricholic in the understanding of the complex signaling pathways of hepatic lipid abnormalities with type 2 diabetes and a treatment target for this condition.
- Definition ChEBI: Alpha-muricholic acid is a member of the class of muricholic acids in which the hydroxy groups at positions 6 and 7 have beta- and alpha- configuration respectively. It is a member of muricholic acids, a 6beta-hydroxy steroid and a 7alpha-hydroxy steroid. It is a conjugate acid of an alpha-muricholate.
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in vivo
Sulfated and non-sulfated bile acids are determined in the intestines and in the feces of 7-month-old germ-free and conventional male mice. The major bile acids from germ-free mice are cholic acid, α-Muricholic acid and β-Muricholic acid[1].
In the context of primary bile acid, α-Muricholic acid is greatly reduced in high-fat diet (HFD)-soybean protein isolate (SPI) mice compared to the HFD controls[2].
α-Muricholic Acid Preparation Products And Raw materials
Raw materials
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2393-58-0, α-Muricholic AcidRelated Search:
- ω-Agatoxin TK Ursodeoxycholic acid Chenodeoxycholic acid 4-[(5S,7S,8S,10S,13R,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid (4R)-4-[(3R,5R,8R,9S,10S,12R,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid URSODEOXYCHOLIC-2,2,4,4-D4 ACID Deoxyursocholic acid methyl ester (5a,7b)-7-hydroxy-3-oxo-Cholan-24-oic acid 7-Oxyisotithocholic Acid 3alpha-Hydroxy-7-oxo-5beta-cholanic Acid LITHOCHOLIC ACID 3,7-DIKETO-5BETA-CHOLAN-24-OIC ACID (3a,5b,7a,12b)-3,7,12-trihydroxy-Cholan-24-oic acid (3α,5β,7β)- 3,7,22-Trihydroxycholan-24-oic Acid (3b,5b,7a,12a)-3,7,12-trihydroxy-Cholan-24-oic acid (4R)-4-[(3S,5S,7S,8S,9S,10R,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid (4R)-4-[(3S,5R,8S,9S,10S,12S,13R,14S)-1,3,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholan-24-oic acid
- Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
- 杂质对照品
- 高端化学
- 临床检测标准物质
- 抑制剂
- 小分子
- 生化试剂
- 熊去氧胆酸杂质79
- Α-鼠胆酸/精确称量
- 化合物 Α-MURICHOLIC ACID
- 5Β-氯酸-3Α,6Β,7Α-三醇
- ALPHA-鼠胆酸 (2,2,3,4,4-D5, 99%)
- 阿尔法-鼠胆酸
- 2H5]-Α-鼠胆酸
- ALPHA-鼠胆酸
- Α-MURICHOLIC ACID
- Α-鼠胆酸
- 熊去氧胆酸杂质29
- Ω-胆酸
- 化合物 T19623
- 2393-58-0
- 5β-CHOLANIC ACID-3α, 6β, 7α-TRIOL
- Cholan-24-oic acid, 3,6,7-trihydroxy-, (3α,5β,6β,7α)-
- 2H5]-α-Muricholic Acid
- DKPMWHFRUGMUKF-GDYCBZMLSA-N
- alfa-Muricholic Acid
- α-Muricholic Acid
- Ursodeoxycholic Acid Impurity 29
- alpha-Muricholate
- a-Muricholic acid
- (3a,5b,6b,7a)-3,6,7-trihydroxy-Cholan-24-oic acid
