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fenetylline hydrochloride

fenetylline hydrochloride Structure
fenetylline hydrochloride
  • CAS No.1892-80-4
  • Chemical Name:fenetylline hydrochloride
  • CBNumber:CB0906063
  • Molecular Formula:C18H24ClN5O2
  • Formula Weight:377.86846
  • MOL File:1892-80-4.mol
fenetylline hydrochloride Property
  • Melting point 227-229°; mp 237-239°
  • solubility DMF: 0.3 mg/ml; DMSO: 0.5 mg/ml; PBS (pH 7.2): 10 mg/ml
  • form A crystalline solid
  • FDA UNII YA7K8ADZ2V
  • ATC code N06BA10
Safety
  • Toxicity :LD50 oral in rat: 100mg/kg
  • DEA Controlled Substances :CSCN: 1503
    CAS SCH: I
    NARC: N
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

fenetylline hydrochloride Chemical Properties,Usage,Production

  • Originator Captagon,Homburg,W. Germany,1961
  • Uses CNS stimulant. Controlled substance.
  • Manufacturing Process 1 mol of 7-(β-chloroethyl)-theophylline and 2? mols of α-methyl-β-phenyl ethylamine are heated for 6 hours in an oil bath, if necessary with addition of alcohol or toluene. The reaction mixture is diluted with alcohol and acidified with alcoholic hydrochloric acid. The crystalline mass formed is filtered with suction and extracted by boiling with alcohol. A product having a melting point of 237°C to 239°C is formed. With prolonged extraction by boiling with alcohol, the melting point of the mass falls, preferably due to a change in modification, to 227°C to 229°C. However, analysis shows that both products are the pure condensation product.
    Instead of the chloroethyl theophylline, it is also possible to use the corresponding bromine derivative. It was found that in this way the process is facilitated and the yield is improved
  • Therapeutic Function Central stimulant
fenetylline hydrochloride Preparation Products And Raw materials
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fenetylline hydrochloride Spectrum
1892-80-4, fenetylline hydrochlorideRelated Search:
  • Pharmaceuticals
  • Nucleotides
  • Intermediates & Fine Chemicals
  • Bases & Related Reagents
  • Aromatics
  • Amines
  • C18H24ClN5O2
  • 芬乙茶碱
  • 1892-80-4
  • fenetylline hydrochloride USP/EP/BP
  • MVXGSLGVWBVZCA-UHFFFAOYSA-N
  • NSC 169872
  • Biocapton
  • 7-[2-[(α-Methylphenethyl)aMino]ethyl]theophylline Hydrochloride
  • 3,7-Dihydro-1,3-diMethyl-7-[2-[(1-Methyl-2-phenylethyl)aMino]ethyl]-1H-purine-2,6-dione Hydrochloride
  • Captagon hydrochloride
  • Amfetyline hydrochloride
  • 7-[2-[(.alpha.-Methylphenethyl)amino]ethyl]theophylline monohydrochloride
  • 7-[2-[(.alpha.-Methylphenethyl)amino]ethyl]theophylline hydrochloride
  • 7-[2-(1-Methyl-2-phenylethylamino)ethyl]theophylline hydrochloride
  • 7-(Phenyl-isopropyl-amino-aethyl)-theophyllin-hydrochlorid
  • 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-7-[2-[(1-methyl-2-phenylethyl)amino]ethyl]-, monohydrochloride
  • Fenethylline hydrochloride
  • Fenetylline
  • Fenethylline
  • fenetylline hydrochloride

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