4-hydroxy (S)-Duloxetine β-D-Glucuronide (sodium salt)

Description

4-hydroxy (S)-Duloxetine β-D-glucuronide is an inactive metabolite of the serotonin and norepinephrine reuptake inhibitor (S)-duloxetine (Item No. 14317).1 It is formed via metabolism of (S)-duloxetine by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP2D6 followed by glucuronidation.WARNING This product is not for human or veterinary use.

References

[1] MARY PAT KNADLER. Duloxetine: clinical pharmacokinetics and drug interactions.[J]. Clinical Pharmacokinetics, 2011, 50 5: 281-294. DOI: 10.2165/11539240-000000000-00000