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(2-pyridyldithio)-PEG4-alcohol

(2-pyridyldithio)-PEG4-alcohol Structure
(2-pyridyldithio)-PEG4-alcohol
  • CAS No.851961-99-4
  • Chemical Name:(2-pyridyldithio)-PEG4-alcohol
  • CBNumber:CB04849380
  • Molecular Formula:C13H21NO4S2
  • Formula Weight:319.44
  • MOL File:851961-99-4.mol
(2-pyridyldithio)-PEG4-alcohol Property
  • solubility Soluble in DMSO, DCM, DMF
  • form Liquid
  • color Colorless to light yellow
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

(2-pyridyldithio)-PEG4-alcohol Chemical Properties,Usage,Production

  • Description (2-pyridyldithio)-PEG2-alcohol is a PEG linker which contains a pyridyl disulfide moiety and an alcohol group. The pyridyl disulfide group can react with thiol groups of proteins over a wide range of pH level. The hydroxyl group allows for further derivatization of the compound. The hydrophilic PEG linker increases the water solubility of the compound.
  • Uses (2-Pyridyldithio)-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
  • IC 50 PEGs
  • References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
(2-pyridyldithio)-PEG4-alcohol Preparation Products And Raw materials
Raw materials
Preparation Products
(2-pyridyldithio)-PEG4-alcohol Suppliers
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(2-pyridyldithio)-PEG4-alcohol Spectrum
851961-99-4, (2-pyridyldithio)-PEG4-alcoholRelated Search:
  • 抑制剂
  • 化合物 (2-PYRIDYLDITHIO)-PEG4-ALCOHOL
  • (2-吡啶基二硫代)-四聚乙二醇-醇
  • 851961-99-4
  • 2-(2-(2-(2-(pyridin-2-yldisulfaneyl)ethoxy)ethoxy)ethoxy)ethan-1-ol
  • Ethanol, 2-[2-[2-[2-(2-pyridinyldithio)ethoxy]ethoxy]ethoxy]-
  • (2-pyridyldithio)-PEG4-alcohol

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