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Boc-L-Tyr(tBu)-OH

Boc-L-Tyr(tBu)-OH Structure
Boc-L-Tyr(tBu)-OH
  • CAS No.47375-34-8
  • Chemical Name:Boc-L-Tyr(tBu)-OH
  • CBNumber:CB0434634
  • Molecular Formula:C18H27NO5
  • Formula Weight:337.41
  • MOL File:47375-34-8.mol
Boc-L-Tyr(tBu)-OH Property
  • Melting point 113-118 °C
  • alpha -15 º (C=1% IN DMF)
  • Boiling point 484.0±40.0 °C(Predicted)
  • Density 1.116±0.06 g/cm3(Predicted)
  • storage temp. 2-8°C
  • solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
  • form powder to crystal
  • pka 3.00±0.10(Predicted)
  • color White to Almost white
  • optical activity [α]20/D 15.0±1.0°, c = 1% in DMF
  • Water Solubility Soluble in DMF. Insoluble in water.
  • BRN 4327336
  • InChI InChI=1S/C18H27NO5/c1-17(2,3)23-13-9-7-12(8-10-13)11-14(15(20)21)19-16(22)24-18(4,5)6/h7-10,14H,11H2,1-6H3,(H,19,22)(H,20,21)/t14-/m0/s1
  • InChIKey ZEQLLMOXFVKKCN-AWEZNQCLSA-N
  • SMILES C(O)(=O)[C@H](CC1=CC=C(OC(C)(C)C)C=C1)NC(OC(C)(C)C)=O
  • CAS DataBase Reference 47375-34-8(CAS DataBase Reference)
  • UNSPSC Code 12352209
  • NACRES NA.22
Safety
  • WGK Germany  :3
  • HS Code  :29242990
  • NFPA 704:
    1
    0 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
Boc-L-Tyr(tBu)-OH Price More Price(7)
  • Brand: Sigma-Aldrich(India)
  • Product number: 8.53023
  • Product name : Boc-Tyr(tBu)-OH
  • Purity: Novabiochem?
  • Packaging: 5G
  • Price: ₹13280
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 8.53023
  • Product name : Boc-Tyr(tBu)-OH
  • Purity: Novabiochem?
  • Packaging: 25G
  • Price: ₹52749.99
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 15434
  • Product name : Boc-Tyr(tBu)-OH
  • Purity: ≥99.0% (sum of enantiomers, TLC)
  • Packaging: 5G
  • Price: ₹12578.65
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: B3485
  • Product name : N-(tert-Butoxycarbonyl)-O-tert-butyl-L-tyrosine
  • Purity: 
  • Packaging: 1G
  • Price: ₹3300
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: B3485
  • Product name : N-(tert-Butoxycarbonyl)-O-tert-butyl-L-tyrosine
  • Purity: 
  • Packaging: 5G
  • Price: ₹10400
  • Updated: 2022/05/26
  • Buy: Buy

Boc-L-Tyr(tBu)-OH Chemical Properties,Usage,Production

  • Chemical Properties White powder
  • Uses N-Boc-O-tert-butyl-L-tyrosine (Boc-L-Tyr(tBu)-OH) is used as pharmaceutical intermediate.
  • Application Boc-Tyr(tBu)-OH is an important organic reagent that can be used as a building block for the synthesis of many organic compounds. This compound could be used as a starting material to synthesize TPE-Tyr. TPE-Tyr can undergo covalent crosslinking via the formation of dityrosine linkages by exploiting horseradish peroxidase (HRP)-catalyzed phenol polymerization in the presence of H2O2, thereby activating the AIE process and switching on fluorescence emission of TPE core motif[1].
  • reaction suitability reaction type: Boc solid-phase peptide synthesis
  • Synthesis O-tert-butyl-L-tyrosine (2.00 g, 8.42 mmol, 1.0 equiv.) and di-tert-butyl dicarbonate (2.20 g, 10.10 mmol, 1.2 equiv.) were dissolved in a mixture of THF (15 mL) and NaOH (1 N, 30 mL) and stirred at room temperature for 10 h. THF was removed under reduced pressure, and the pH of residual solution was adjusted to 3.0 with dilute hydrochloric acid and the crude product was extracted by ethyl acetate. The combined organic phases was washed with saturated brine (pH 3.0) and dried over anhydrous Na2SO4. The organic solvent was removed under reduced pressure and dried in a vacuum oven at room temperature overnight, affording (N-Boc-O-tert-butyl)-L-Tyr (Boc-O-tert-butyl-L-tyrosine) as a yellowish solid (2.64 g, 93%)[1].
    Boc-O-tert-butyl-L-tyrosine
  • References [1] Wang X, et al. Highly Selective Fluorogenic Multianalyte Biosensors Constructed via Enzyme-Catalyzed Coupling and Aggregation-Induced Emission. Journal of the American Chemical Society, 2014; 136: 9890–9893.
Boc-L-Tyr(tBu)-OH Preparation Products And Raw materials
Raw materials
Preparation Products
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Boc-L-Tyr(tBu)-OH Spectrum
47375-34-8, Boc-L-Tyr(tBu)-OHRelated Search:
  • Amino Acids
  • Boc-Amino acid series
  • Boc-Amino Acids and Derivative
  • 氨基酸
  • 有机原料
  • 抑制剂
  • 保护氨基酸(AA)-酪氨酸(Tyr)
  • 生化试剂
  • 化学试剂
  • 保护氨基酸系列-BOC及其他氨基酸
  • 氨基酸衍生物
  • Boc-保护氨基酸
  • 保护氨基酸
  • 化学生物学
  • Boc保护氨基酸
  • 胺基酸
  • Amino Acid Derivatives
  • Tyrosine
  • Specialty Synthesis
  • Peptide Synthesis
  • CARBOXYLIC ACID
  • C18H27NO5
  • CH33COC6H4CH2CHCOOHNHCOOCCH33
  • 化合物 BOC-TYR(TBU)-OH
  • PERFEMIKER]BOC-O-叔丁基-L-酪氨酸,99%
  • BOC-0-叔丁基-L-酪氨酸
  • (S)-3-(4-(叔丁氧基)苯基)-2-((叔丁氧基羰基)氨基)丙酸
  • N-(TERT-BUTOXYCARBONYL)-O-TERT-BUTYL-L-TYROSINE N-(叔丁氧羰基)-O-叔丁基-L-酪氨酸
  • BOC-O-叔丁基-L-酪氨酸, 99.0%
  • 丁氧羰基-酪氨酸(叔溴尿嘧啶)
  • N-叔丁氧羰基-O-叔丁基-L-酪氨酸
  • BOC-O-叔丁基-L-酪氨酸
  • N-BOC-O-叔丁基-L-酪氨酸
  • 47375-34-8
  • BOC-0-tert-butyl-L-tyrosine
  • Boc-Tyr(tBu)
  • BOC-TYR(TBU)-OH
  • BOC-L-TYR(TBU)-OH
  • (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]propanoic acid
  • Boc-O-tert-butyl-L-tyrosine USP/EP/BP
  • L-Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-O-(1,1-dimethylethyl)-
  • N-(tert-Butoxycarbonyl)-O-tert-butyl-L-tyrosine &gt
  • (Tert-Butoxy)Carbonyl Tyr(tBu)-OH
  • Boc-Tyr(tBu)-OH, 99.0%
  • (2S)-2-{[(tert-butoxy)carbonyl]amino}-3-[4-(tert-butoxy)phenyl]propanoic acid
  • (2S)-2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]propanoic acid
  • Boc-O-tert-butyl-L-tyrosine≥ 99% (HPLC)
  • (S)-2-(Boc-amino)-3-(4-tert-butoxyphenyl)propionic acid
  • Boc-Tyr(tBu)-OH 100g
  • N-Boc-O-tert-butyl-L-tyrosine, 98%
  • (S)-3-(4-(tert-Butoxy)phenyl)-2-((tert-butoxycarbonyl)aMino)propanoic acid
  • N-Boc-O-tert-butyl-L-tyrosine Boc-Tyr(tBu)-OH
  • Boc-L-tyrosine beta-tert-butyl ester
  • (S)-2-(tert-butoxycarbonylamino)-3-(4-tert-butoxyphenyl)propanoic acid
  • N-ALPHA-T-BUTYLOXYCARBONYL-O-T-BUTYL-L-TYROSINE
  • Boc-Tyr(tBul)-OH
  • N-tert-Butoxycarbonyl-O-tert-butyl-L-tyrosine
  • N-ALPHA-T-BUTOXYCARBONYL-O-T-BUTYL-L-TYROSINE