ChemicalBook > CAS DataBase List > N,N-Dimethylpiperidin-4-amine
N,N-Dimethylpiperidin-4-amine
N,N-Dimethylpiperidin-4-amine
- CAS No.50533-97-6
- Chemical Name:N,N-Dimethylpiperidin-4-amine
- CBNumber:CB0394628
- Molecular Formula:C7H16N2
- Formula Weight:128.22
- MOL File:50533-97-6.mol
N,N-Dimethylpiperidin-4-amine Property
- Boiling point 187°C
- Density 1.09g/ml
- Flash point 187°C
- refractive index 1.4760
- storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
- form liquid
- pka 10.10±0.10(Predicted)
- color Clear, colourless
- BRN 1190
- CAS DataBase Reference 50533-97-6(CAS DataBase Reference)
- UNSPSC Code 12352200
Safety
- Hazard Codes :Xi,Xn
- Risk Statements :10-34-22
- Safety Statements :26-36/37/39-45
- RIDADR :2734
- Hazard Note :Irritant
- HazardClass :8
- PackingGroup :III
- HS Code :2933399990
-
NFPA 704:
0 1 0
-
Symbol(GHS)
- Signal wordDanger
- Hazard statements H314-H318
- Precautionary statements P260h-P301+P330+P331-P303+P361+P353-P305+P351+P338-P405-P501a
N,N-Dimethylpiperidin-4-amine Chemical Properties,Usage,Production
- Uses 4-(Dimethylamino)piperidine is having molecular features associated with polyamine modulation of N-methyl-D-aspartate receptors. It is utilized as a mechanism for reducing the effects of alcohol dependence.
-
Synthesis
1-(tert-Butoxycarbonyl)-4-piperidone (998 mg, 4.75 mmol) in methanol (15 mL) was treated with dimethylamine hydrochloride (800 mg, 9.8 mmol) and sodium cyanoborohydride (270 mg, 4.3 mmol) at rt. After 4 days, concentrated HCl (10 mL) was added and the reaction was reduced in vacuo. The resulting residue was dissolved in H2O (30 mL) and treated with 2M NaOH solution to achieve a pH of 10. The aqueous solution was extracted with methylene chloride (3×20 mL) and the combined organics were dried over Na2SO4 and removed in vacuo. The resulting product is N,N-Dimethylpiperidin-4-amine (169 mg). - storage Incompatible with air, water, oxidizing agents and heat.
N,N-Dimethylpiperidin-4-amine Preparation Products And Raw materials
Raw materials
Preparation Products
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50533-97-6, N,N-Dimethylpiperidin-4-amineRelated Search:
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- 50533-97-6
- N,N-4-Dimethyl amino piperidine
- DIMETHYL-PIPERIDIN-4-YL-AMINE
- N,N-Dimethylpiperidin-4-amine USP/EP/BP
- 4-Piperidinamine, N,N-dimethyl-
- N,N-Dimethylpiperidin-4-amin
- EOS-60858
- N,N-DiMethylpiperidin-4-aMine 2HCl
- N,N-dimethylpiperidin-4-amine(SALTDATA: FREE)
- N,N-Dimethylpiperidin-4-amine hydrochloride
- N,N''-DIMETHYLAMINOPIPERIDINE
- 4-DIMETHYLAMINO-PIPERIDINE 98%
- N,N-Dimethylpiperidine-4-amine
- N,N-Dimethyl-4-piperidinamine
- 4-(Dimethylamino)piperidine,98%
- CHEMBRDG-BB 4018153
- 4-DIMETHYLAMINO-PIPERIDINE
- 4-(N,N-DIMETHYLAMINO)PIPERIDINE
- AKOS BB-9178
- N,N-DIMETHYLPIPERIDIN-4-AMINE