ChemicalBook > CAS DataBase List > Acid-PEG2-t-butyl ester

Acid-PEG2-t-butyl ester

Acid-PEG2-t-butyl ester Structure
Acid-PEG2-t-butyl ester
  • CAS No.2086688-99-3
  • Chemical Name:Acid-PEG2-t-butyl ester
  • CBNumber:CB03303326
  • Molecular Formula:C12H22O6
  • Formula Weight:262.3
  • MOL File:2086688-99-3.mol
Acid-PEG2-t-butyl ester Property
  • Boiling point 384.3±27.0 °C(Predicted)
  • Density 1.104±0.06 g/cm3(Predicted)
  • solubility Soluble in Water, DMSO, DMF
  • pka 4.27±0.10(Predicted)
  • form Liquid
  • color Colorless to light yellow
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H335
  • Precautionary statements P261-P280-P301+P312-P302+P352-P305+P351+P338

Acid-PEG2-t-butyl ester Chemical Properties,Usage,Production

  • Description Acid-PEG2-t-butyl ester is a PEG linker containing a t-butyl protected carboxyl group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
  • Uses Acid-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
  • IC 50 PEGs; Alkyl/ether
  • References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Acid-PEG2-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
Acid-PEG2-t-butyl ester Suppliers
Global(64)Suppliers
  • Supplier：
    Accela ChemBio Inc.
  • Tel：+1-858-6993322
  • Email：info@accelachem.com
  • Country：United States
  • ProdList：19825
  • Advantage：58
  • Supplier：
    TargetMol Chemicals Inc.
  • Tel：+1-781-999-5354<br/>+1-00000000000
  • Email：marketing@targetmol.com
  • Country：United States
  • ProdList：32159
  • Advantage：58
  • Supplier：
    Wuhan Borenpharm Co., Ltd
  • Tel：027-65563561<br/>18717150066
  • Email：3207347307@qq.com
  • Country：CHINA
  • ProdList：1238
  • Advantage：58
  • Supplier：
    Nextpeptide Inc
  • Tel：+86-0571-81612335<br/>+8613336028439
  • Email：sales@nextpeptide.com
  • Country：China
  • ProdList：19908
  • Advantage：58
  • Supplier：
    TargetMol Chemicals Inc.
  • Tel：
  • Email：support@targetmol.com
  • Country：United States
  • ProdList：38630
  • Advantage：58
  • Supplier：
    LEAPCHEM CO., LTD.
  • Tel：+86-852-30606658
  • Email：market18@leapchem.com
  • Country：China
  • ProdList：43340
  • Advantage：58
Acid-PEG2-t-butyl ester Spectrum
2086688-99-3, Acid-PEG2-t-butyl esterRelated Search:
  • peg
  • 抑制剂
  • PEG系列产品-Acid-PEG系列
  • 高端化学
  • 助剂
  • 化合物 ACID-PEG2-C2-BOC
  • 3-[2-(2-BOC-乙氧基)乙氧基]丙酸
  • 丙酸-PEG2-丙酸叔丁酯
  • 羧酸-二聚乙二醇-丙酸叔丁酯
  • 3-(2-(3-(叔丁氧基)-3-氧代丙氧基)乙氧基)丙酸
  • 羧酸-一聚乙二醇-丙酸叔丁酯
  • 丙酸,3-[2-(2-羧乙氧基)乙氧基]-,1-(1,1-二甲基乙基)酯
  • 丙酸二聚乙二醇丙酸叔丁酯
  • 甲酸-聚乙二醇-丙酸叔丁酯
  • 2086688-99-3
  • 3-[2-(2-Boc-ethoxy)ethoxy]propanoic Acid
  • Acid-PEG2-t-Bu Ester
  • 3-(2-(3-(tert-Butoxy)-3-oxopropoxy)ethoxy)propanoic acid
  • t-butyl ester-PEG1-acid
  • Acid-PEG2-C2-Boc
  • Propanoic acid, 3-[2-(2-carboxyethoxy)ethoxy]-, 1-(1,1-dimethylethyl) ester
  • COOH-PEG2-OtBu
  • 3-[2-(2-Carboxyethoxy)ethoxy]propanoic acid tert-butyl ester
  • Acid-PEG2-t-butyl ester

Home

My