ChemicalBook > CAS DataBase List > IDO-IN-3
IDO-IN-3
IDO-IN-3
- CAS No.2070018-30-1
- Chemical Name:IDO-IN-3
- CBNumber:CB03041413
- Molecular Formula:C11H12BrFN6O2
- Formula Weight:359.15
- MOL File:2070018-30-1.mol
IDO-IN-3 Property
- Boiling point 570.8±60.0 °C(Predicted)
- Density 1.86±0.1 g/cm3(Predicted)
- storage temp. Store at -20°C
- solubility Ethanol: 1 mg/ml
- form A crystalline solid
- pka 7?+-.0.69(Predicted)
- color White to off-white
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
IDO-IN-3 Chemical Properties,Usage,Production
- Description IDO-IN-3 is an inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1; IC50s = 290 and 98 nM for the human recombinant enzyme in a cell-free assay and in HeLa cells, respectively).
- Uses IDO-IN-3 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 290 nM.
- IC 50 IDO: 290 nM (IC50); IDO: 98 nM (IC50, in HeLa cell)
- References [1] Yue EW, et al. INCB24360 (Epacadostat), a Highly Potent and Selective Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitor for Immuno-oncology. ACS Med Chem Lett. 2017 Mar 6;8(5):486-491. DOI:10.1021/acsmedchemlett.6b00391
IDO-IN-3 Preparation Products And Raw materials
Raw materials
Preparation Products
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2070018-30-1, IDO-IN-3Related Search:
- 抑制剂
- C11H12BrFN6O2
- 化合物 IDO-IN-3
- 化合物 T11617
- 2070018-30-1
- IDO IN 3,IDOIN3
- 1,2,5-Oxadiazole-3-carboximidamide, 4-[(2-aminoethyl)amino]-N'-(3-bromo-4-fluorophenyl)-N-hydroxy-
- IDO inhibitor 3
- IDO-IN-3