4-(2-aminopropyl)phenol

Uses

p-Hydroxyamphetamine is a major metabolite of Amphetamine (A634240), a sympathomimetic and psychotropic drug which is extensively metabolized in liver and in brain.

Definition

ChEBI: 4-(2-aminopropyl)phenol is a member of amphetamines.

Purification Methods

Crystallise the phenol from *benzene. The R-(-)-enantiomer crystallises from EtOH or *C6H6 with m 110.5-111.5o and []17 -52.0o (c 1, EtOH). The (±)-hydrochloride has m 171-172o (EtOH/Et2O), and the 2,4-dinitrophenylhydrazone has m 190-192o (EtOH). [Beilstein 13 I 251, 13 III 1709, 13 IV 1871.]