Anticancer Research
C. serratum (family, Verbenaceae) is commonly known as bharangi (Poornima et al.2015). It is widely spread across tropics, subtropics, and deciduous forests of theWestern Ghats of India. As per the traditional claims, the roots and leaves of bharangihave prodigious therapeutic value. The plant is useful both internally andexternally for various medicinal trails (Nagdeva and Singh 2012). Ethnomedicinalimportance of the plant has been reported in various folk medical practices includingAyurveda, Unani, and Siddha for treating many serious health issues such astyphoid, syphilis, jaundice, hypertension, and cancer (Poornima et al. 2015). Someof the chief constituents found in the plant are D-mannitol, hispidulin, cleroflavone,apigenin, scutellarein, serratagenic acid, acteoside, verbascoside, oleanolic acid,clerodermic acid, γ-sitosterol, β-sitosterol, cholestanol, clerosterol, campesterol,and 24-ethylcholesterol (Poornima et al. 2015). Traditionally, it has been also usedas antirheumatic, antiasthmatic, febrifuge, encephalagia, and ophthalmia. The roots of C. serratum are also used as antioxidant, antibacterial, and antifungal. Besidesthese the antimicrobial value of this herbal plant has also been reported in its stemsand leaves. These reports are very encouraging and indicate that herb should bestudied more expensively for its therapeutic benefits. The plant root extract is shownto prevent Dalton’s Ascetic Lymphoma in mice (Zalke et al. 2010; Nagdeva andSingh 2012).
